4Y71

Factor Xa complex with GTC000398

Summary for 4Y71

DescriptorCoagulation factor X, CALCIUM ION, 6-chloro-N-{(3S)-1-[(2S)-1-(4-methyl-5-oxo-1,4-diazepan-1-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}naphthalene-2-sulfonamide, ... (5 entities in total)
Functional Keywordshydrolase, inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationSecreted P00742 P00742
Total number of polymer chains2
Total molecular weight44308.47
Authors
Convery, M.A.,Young, R.J.,Senger, S.,Hamblin, J.N.,Chan, C.,Toomey, J.R.,Watson, N.S. (deposition date: 2015-02-13, release date: 2015-09-30)
Primary citation
Convery, M.A.,Young, R.J.,Senger, S.,Hamblin, J.N.,Chan, C.,Toomey, J.R.,Watson, N.S.
Factor Xa complex with GTC000398
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.240300.8%7.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report