5FMA
human Notch 1, EGF 4-7
Summary for 5FMA
Entry DOI | 10.2210/pdb5fma/pdb |
Related | 5FM9 |
Descriptor | NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, CALCIUM ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | transcription, transmembrane, developmental, protein, notch signaling pathway, differentiation, phosphorylation, egf- like domain, regulation, receptor, activator, ank repeat, signalling, glycoprotein, extracellular, egf, notch, jagged, membrane |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cell membrane ; Single-pass type I membrane protein . Notch 1 intracellular domain: Nucleus : P46531 |
Total number of polymer chains | 2 |
Total formula weight | 33161.63 |
Authors | Weisshuhn, P.C.,Sheppard, D.,Taylor, P.,Whiteman, P.,Lea, S.M.,Handford, P.A.,Redfield, C. (deposition date: 2015-11-02, release date: 2016-04-13, Last modification date: 2024-01-10) |
Primary citation | Weisshuhn, P.C.,Sheppard, D.,Taylor, P.,Whiteman, P.,Lea, S.M.,Handford, P.A.,Redfield, C. Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies. Structure, 24:555-, 2016 Cited by PubMed: 26996961DOI: 10.1016/J.STR.2016.02.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.46 Å) |
Structure validation
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