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1T2D
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Plasmodium falciparum lactate dehydrogenase complexed with NAD+ and oxalate
分子名称: GLYCEROL, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G.
登録日2004-04-21
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
1T2E
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Plasmodium falciparum lactate dehydrogenase S245A, A327P mutant complexed with NADH and oxamate
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-lactate dehydrogenase, ...
著者Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G.
登録日2004-04-21
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
1T2F
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Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid
分子名称: 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase B chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G.
登録日2004-04-21
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279, 2004
1T2H
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Y81W mutant of RNase Sa from Streptomyces aureofaciens
分子名称: Guanyl-specific ribonuclease Sa, SULFATE ION
著者Sevcik, J, Urbanikova, L.
登録日2004-04-21
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Contribution of single tryptophan residues to the fluorescence and stability of ribonuclease sa.
Biophys.J., 87, 2004
1T2I
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T76W mutant of RNase Sa from Streptomyces aureofaciens
分子名称: Guanyl-specific ribonuclease Sa
著者Urbanikova, L, Sevcik, J.
登録日2004-04-21
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Contribution of single tryptophan residues to the fluorescence and stability of ribonuclease sa.
Biophys.J., 87, 2004
1T2J
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Crystal structure of a Human VH domain
分子名称: DI(HYDROXYETHYL)ETHER, M12-Variable Heavy domain
著者Gaur, R.K, Fischer, R, Hoffmann, K.M.V.
登録日2004-04-21
公開日2005-05-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a human VH domain at 1.5 angstrom
To be Published
1T2K
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Structure Of The DNA Binding Domains Of IRF3, ATF-2 and Jun Bound To DNA
分子名称: 31-MER, Cyclic-AMP-dependent transcription factor ATF-2, Interferon regulatory factor 3, ...
著者Panne, D, Maniatis, T, Harrison, S.C.
登録日2004-04-21
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer.
Embo J., 23, 2004
1T2L
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Three Crystal Structures of Human Coactosin-like Protein
分子名称: Coactosin-like protein
著者Liu, L, Wei, Z, Chen, Z, Wang, Y, Gong, W.
登録日2004-04-22
公開日2004-11-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Human Coactosin-like Protein
J.Mol.Biol., 344, 2004
1T2M
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Solution Structure Of The Pdz Domain Of AF-6
分子名称: AF-6 protein
著者Zhou, H, Wu, J.H, Xu, Y.Q, Huang, A.D, Shi, Y.Y.
登録日2004-04-22
公開日2005-02-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of AF-6 PDZ Domain and Its Interaction with the C-terminal Peptides from Neurexin and Bcr
J.Biol.Chem., 280, 2005
1T2N
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Structure of a thermostable triple mutant of Bacillus subtilis lipase obtained through directed evolution
分子名称: Lipase, POTASSIUM ION
著者Rajakumara, E, Sankaranarayanan, R.
登録日2004-04-22
公開日2004-11-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase.
J.Mol.Biol., 341, 2004
1T2O
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Crystal structure of Se-SrtA, C184-Ala
分子名称: sortase
著者Zong, Y, Bice, T.W, Ton-That, H, Schneewind, O, Narayana, S.V.
登録日2004-04-22
公開日2004-09-07
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of Staphylococcus aureus sortase A and its substrate complex
J.Biol.Chem., 279, 2004
1T2P
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Crystal structure of Sortase A from Staphylococcus aureus
分子名称: sortase
著者Zong, Y, Bice, T.W, Ton-That, H, Schneewind, O, Narayana, S.V.
登録日2004-04-22
公開日2004-09-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献CRYSTAL STRUCTURES OF STAPHYLOCOCCUS AUREUS SORTASE A AND ITS SUBSTRATE COMPLEX
J.Biol.Chem., 279, 2004
1T2Q
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The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Fab NNA7 Heavy Chain, Fab NNA7 Light Chain, ...
著者Xie, K, Song, S.C, Spitalnik, S.L, Wedekind, J.E.
登録日2004-04-22
公開日2005-06-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Crystal Structure and Mutational Analysis of an Antibody that Recognizes an N-type Blood Group Antigen
To be Published
1T2R
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Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
分子名称: 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2
著者Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
登録日2004-04-22
公開日2004-06-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1T2S
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Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
分子名称: 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2
著者Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
登録日2004-04-22
公開日2004-06-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1T2T
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Crystal structure of the DNA-binding domain of intron endonuclease I-TevI with operator site
分子名称: 5'-D(*AP*AP*TP*TP*AP*AP*AP*GP*GP*GP*CP*AP*GP*TP*CP*CP*TP*AP*CP*AP*A)-3', 5'-D(*TP*TP*TP*GP*TP*AP*GP*GP*AP*CP*TP*GP*CP*CP*CP*TP*TP*TP*AP*AP*T)-3', Intron-associated endonuclease 1, ...
著者Edgell, D.R, Derbyshire, V, Van Roey, P, LaBonne, S, Stanger, M.J, Li, Z, Boyd, T.M, Shub, D.A, Belfort, M.
登録日2004-04-22
公開日2004-09-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor.
Nat.Struct.Mol.Biol., 11, 2004
1T2U
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Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
著者Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M.
登録日2004-04-22
公開日2004-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
1T2V
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Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide
分子名称: BRCTide-7PS, Breast cancer type 1 susceptibility protein
著者Williams, R.S, Lee, M.S, Hau, D.D, Glover, J.N.M.
登録日2004-04-22
公開日2004-05-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
1T2W
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Crystal Structure of Sortase A in Complex with a LPETG peptide
分子名称: Class A sortase SrtA, Peptide LEU-PRO-GLU-THR-GLY
著者Zong, Y, Bice, T.W, Ton-That, H, Schneewind, O, Narayana, S.V.
登録日2004-04-23
公開日2004-09-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of Staphylococcus aureus sortase A and its substrate complex
J.Biol.Chem., 279, 2004
1T2X
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Glactose oxidase C383S mutant identified by directed evolution
分子名称: ACETATE ION, COPPER (II) ION, Galactose Oxidase, ...
著者Wilkinson, D, Akumanyi, N, Hurtado-Guerrero, R, Dawkes, H, Knowles, P.F, Phillips, S.E.V, McPherson, M.J.
登録日2004-04-23
公開日2004-05-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and kinetic studies of a series of mutants of galactose oxidase identified by directed evolution.
Protein Eng.Des.Sel., 17, 2004
1T2Y
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NMR solution structure of the protein part of Cu6-Neurospora crassa MT
分子名称: Metallothionein
著者Cobine, P.A, McKay, R.T, Zangger, K, Dameron, C.T, Armitage, I.M.
登録日2004-04-23
公開日2004-11-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Cu metallothionein from the fungus Neurospora crassa
Eur.J.Biochem., 271, 2004
1T31
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A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E, Pereira, P.J.B, Wang, Z.M, Rubin, H, Huber, R, Bode, W, Schechter, N.M, Strobl, S.
登録日2004-04-23
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
J.Biol.Chem., 280, 2005
1T32
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A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation
分子名称: 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, Cathepsin G, SULFATE ION
著者de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E.
登録日2004-04-23
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
J.Biol.Chem., 280, 2005
1T33
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Structural Genomics, The crystal structure of a putative transcriptional repressor (TetR/AcrR family) from Salmonella typhimurim LT2
分子名称: putative transcriptional repressor (TetR/AcrR family)
著者Zhang, R, Zhou, M, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2004-04-23
公開日2004-08-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of a putative transcriptional repressor (TetR/AcrR family) from Salmonella typhimurium
To be Published
1T34
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ROTATION MECHANISM FOR TRANSMEMBRANE SIGNALING BY THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Atrial natriuretic peptide factor, Atrial natriuretic peptide receptor A, ...
著者Ogawa, H, Qiu, Y, Ogata, C.M, Misono, K.S.
登録日2004-04-23
公開日2004-08-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of hormone-bound atrial natriuretic peptide receptor extracellular domain: rotation mechanism for transmembrane signal transduction
J.Biol.Chem., 279, 2004

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