1T2D
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![BU of 1t2d by Molmil](/molmil-images/mine/1t2d) | Plasmodium falciparum lactate dehydrogenase complexed with NAD+ and oxalate | 分子名称: | GLYCEROL, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-21 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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1T2E
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![BU of 1t2e by Molmil](/molmil-images/mine/1t2e) | Plasmodium falciparum lactate dehydrogenase S245A, A327P mutant complexed with NADH and oxamate | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-lactate dehydrogenase, ... | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-21 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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1T2F
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![BU of 1t2f by Molmil](/molmil-images/mine/1t2f) | Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid | 分子名称: | 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase B chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-21 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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1T2H
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![BU of 1t2h by Molmil](/molmil-images/mine/1t2h) | |
1T2I
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![BU of 1t2i by Molmil](/molmil-images/mine/1t2i) | |
1T2J
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1T2K
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![BU of 1t2k by Molmil](/molmil-images/mine/1t2k) | Structure Of The DNA Binding Domains Of IRF3, ATF-2 and Jun Bound To DNA | 分子名称: | 31-MER, Cyclic-AMP-dependent transcription factor ATF-2, Interferon regulatory factor 3, ... | 著者 | Panne, D, Maniatis, T, Harrison, S.C. | 登録日 | 2004-04-21 | 公開日 | 2004-11-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. Embo J., 23, 2004
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1T2L
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![BU of 1t2l by Molmil](/molmil-images/mine/1t2l) | Three Crystal Structures of Human Coactosin-like Protein | 分子名称: | Coactosin-like protein | 著者 | Liu, L, Wei, Z, Chen, Z, Wang, Y, Gong, W. | 登録日 | 2004-04-22 | 公開日 | 2004-11-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of Human Coactosin-like Protein J.Mol.Biol., 344, 2004
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1T2M
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![BU of 1t2m by Molmil](/molmil-images/mine/1t2m) | Solution Structure Of The Pdz Domain Of AF-6 | 分子名称: | AF-6 protein | 著者 | Zhou, H, Wu, J.H, Xu, Y.Q, Huang, A.D, Shi, Y.Y. | 登録日 | 2004-04-22 | 公開日 | 2005-02-08 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of AF-6 PDZ Domain and Its Interaction with the C-terminal Peptides from Neurexin and Bcr J.Biol.Chem., 280, 2005
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1T2N
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1T2O
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![BU of 1t2o by Molmil](/molmil-images/mine/1t2o) | Crystal structure of Se-SrtA, C184-Ala | 分子名称: | sortase | 著者 | Zong, Y, Bice, T.W, Ton-That, H, Schneewind, O, Narayana, S.V. | 登録日 | 2004-04-22 | 公開日 | 2004-09-07 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of Staphylococcus aureus sortase A and its substrate complex J.Biol.Chem., 279, 2004
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1T2P
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![BU of 1t2p by Molmil](/molmil-images/mine/1t2p) | Crystal structure of Sortase A from Staphylococcus aureus | 分子名称: | sortase | 著者 | Zong, Y, Bice, T.W, Ton-That, H, Schneewind, O, Narayana, S.V. | 登録日 | 2004-04-22 | 公開日 | 2004-09-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | CRYSTAL STRUCTURES OF STAPHYLOCOCCUS AUREUS SORTASE A AND ITS SUBSTRATE COMPLEX J.Biol.Chem., 279, 2004
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1T2Q
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![BU of 1t2q by Molmil](/molmil-images/mine/1t2q) | The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Fab NNA7 Heavy Chain, Fab NNA7 Light Chain, ... | 著者 | Xie, K, Song, S.C, Spitalnik, S.L, Wedekind, J.E. | 登録日 | 2004-04-22 | 公開日 | 2005-06-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal Structure and Mutational Analysis of an Antibody that Recognizes an N-type Blood Group Antigen To be Published
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1T2R
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![BU of 1t2r by Molmil](/molmil-images/mine/1t2r) | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | 分子名称: | 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2 | 著者 | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | 登録日 | 2004-04-22 | 公開日 | 2004-06-01 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat.Struct.Mol.Biol., 11, 2004
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1T2S
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![BU of 1t2s by Molmil](/molmil-images/mine/1t2s) | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | 分子名称: | 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2 | 著者 | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | 登録日 | 2004-04-22 | 公開日 | 2004-06-01 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat.Struct.Mol.Biol., 11, 2004
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1T2T
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![BU of 1t2t by Molmil](/molmil-images/mine/1t2t) | Crystal structure of the DNA-binding domain of intron endonuclease I-TevI with operator site | 分子名称: | 5'-D(*AP*AP*TP*TP*AP*AP*AP*GP*GP*GP*CP*AP*GP*TP*CP*CP*TP*AP*CP*AP*A)-3', 5'-D(*TP*TP*TP*GP*TP*AP*GP*GP*AP*CP*TP*GP*CP*CP*CP*TP*TP*TP*AP*AP*T)-3', Intron-associated endonuclease 1, ... | 著者 | Edgell, D.R, Derbyshire, V, Van Roey, P, LaBonne, S, Stanger, M.J, Li, Z, Boyd, T.M, Shub, D.A, Belfort, M. | 登録日 | 2004-04-22 | 公開日 | 2004-09-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor. Nat.Struct.Mol.Biol., 11, 2004
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1T2U
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![BU of 1t2u by Molmil](/molmil-images/mine/1t2u) | Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F | 分子名称: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION | 著者 | Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M. | 登録日 | 2004-04-22 | 公開日 | 2004-05-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1 Nat.Struct.Mol.Biol., 11, 2004
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1T2V
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![BU of 1t2v by Molmil](/molmil-images/mine/1t2v) | Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide | 分子名称: | BRCTide-7PS, Breast cancer type 1 susceptibility protein | 著者 | Williams, R.S, Lee, M.S, Hau, D.D, Glover, J.N.M. | 登録日 | 2004-04-22 | 公開日 | 2004-05-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1 Nat.Struct.Mol.Biol., 11, 2004
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1T2W
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![BU of 1t2w by Molmil](/molmil-images/mine/1t2w) | Crystal Structure of Sortase A in Complex with a LPETG peptide | 分子名称: | Class A sortase SrtA, Peptide LEU-PRO-GLU-THR-GLY | 著者 | Zong, Y, Bice, T.W, Ton-That, H, Schneewind, O, Narayana, S.V. | 登録日 | 2004-04-23 | 公開日 | 2004-09-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of Staphylococcus aureus sortase A and its substrate complex J.Biol.Chem., 279, 2004
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1T2X
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![BU of 1t2x by Molmil](/molmil-images/mine/1t2x) | Glactose oxidase C383S mutant identified by directed evolution | 分子名称: | ACETATE ION, COPPER (II) ION, Galactose Oxidase, ... | 著者 | Wilkinson, D, Akumanyi, N, Hurtado-Guerrero, R, Dawkes, H, Knowles, P.F, Phillips, S.E.V, McPherson, M.J. | 登録日 | 2004-04-23 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and kinetic studies of a series of mutants of galactose oxidase identified by directed evolution. Protein Eng.Des.Sel., 17, 2004
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1T2Y
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![BU of 1t2y by Molmil](/molmil-images/mine/1t2y) | NMR solution structure of the protein part of Cu6-Neurospora crassa MT | 分子名称: | Metallothionein | 著者 | Cobine, P.A, McKay, R.T, Zangger, K, Dameron, C.T, Armitage, I.M. | 登録日 | 2004-04-23 | 公開日 | 2004-11-23 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Cu metallothionein from the fungus Neurospora crassa Eur.J.Biochem., 271, 2004
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1T31
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![BU of 1t31 by Molmil](/molmil-images/mine/1t31) | A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E, Pereira, P.J.B, Wang, Z.M, Rubin, H, Huber, R, Bode, W, Schechter, N.M, Strobl, S. | 登録日 | 2004-04-23 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J.Biol.Chem., 280, 2005
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1T32
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![BU of 1t32 by Molmil](/molmil-images/mine/1t32) | A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | 分子名称: | 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, Cathepsin G, SULFATE ION | 著者 | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E. | 登録日 | 2004-04-23 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J.Biol.Chem., 280, 2005
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1T33
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1T34
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![BU of 1t34 by Molmil](/molmil-images/mine/1t34) | ROTATION MECHANISM FOR TRANSMEMBRANE SIGNALING BY THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Atrial natriuretic peptide factor, Atrial natriuretic peptide receptor A, ... | 著者 | Ogawa, H, Qiu, Y, Ogata, C.M, Misono, K.S. | 登録日 | 2004-04-23 | 公開日 | 2004-08-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal structure of hormone-bound atrial natriuretic peptide receptor extracellular domain: rotation mechanism for transmembrane signal transduction J.Biol.Chem., 279, 2004
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