4YBH
 
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1LVR
 | | IC3 of CB1 (L431A,A432L) Bound to G(alpha)i | | 分子名称: | Cannabinoid receptor 1 | | 著者 | Ulfers, A.L, McMurry, J.L, Miller, A, Wang, L, Kendall, D.A, Mierke, D.F. | | 登録日 | 2002-05-29 | | 公開日 | 2002-12-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity.
Protein Sci., 11, 2002
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4YMN
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1LWJ
 | | CRYSTAL STRUCTURE OF T. MARITIMA 4-ALPHA-GLUCANOTRANSFERASE/ACARBOSE COMPLEX | | 分子名称: | 4-ALPHA-GLUCANOTRANSFERASE, CALCIUM ION, MODIFIED ACARBOSE PENTASACCHARIDE | | 著者 | Roujeinikova, A, Raasch, C, Sedelnikova, S, Liebl, W, Rice, D.W. | | 登録日 | 2002-05-31 | | 公開日 | 2002-08-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA 4-ALPHA-GLUCANOTRANSFERASE AND ITS ACARBOSE COMPLEX:
IMPLICATIONS FOR SUBSTRATE SPECIFICITY AND CATALYSIS
J.Mol.Biol., 321, 2002
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4YMU
 | | Crystal structure of an amino acid ABC transporter complex with arginines and ATPs | | 分子名称: | ABC-type amino acid transport system, permease component, ABC-type polar amino acid transport system, ... | | 著者 | Ge, J, Yu, J, Yang, M. | | 登録日 | 2015-03-07 | | 公開日 | 2015-04-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | | 主引用文献 | Structural basis for substrate specificity of an amino acid ABC transporter
Proc.Natl.Acad.Sci.USA, 112, 2015
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1LVU
 | | Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit | | 分子名称: | 2,6-DIAMINO-(S)-9-[2-(PHOSPHONOMETHOXY)PROPYL]PURINE, CALCIUM ION, Purine nucleoside phosphorylase | | 著者 | Bzowska, A, Koellner, G, Wielgus-Kutrowska, B, Stroh, A, Raszewski, G, Holy, A, Steiner, T, Frank, J. | | 登録日 | 2002-05-29 | | 公開日 | 2003-09-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis
J.Mol.Biol., 342, 2004
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4YBQ
 | | Rat GLUT5 with Fv in the outward-open form | | 分子名称: | Solute carrier family 2, facilitated glucose transporter member 5, antibody Fv fragment heavy chain, ... | | 著者 | Nomura, N, Shimamura, T, Iwata, S. | | 登録日 | 2015-02-19 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | | 主引用文献 | Structure and mechanism of the mammalian fructose transporter GLUT5
Nature, 526, 2015
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1LX7
 | | Structure of E. coli uridine phosphorylase at 2.0A | | 分子名称: | uridine phosphorylase | | 著者 | Burling, T, Buglino, J.A, Kniewel, R, Chadna, T, Beckwith, A, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2002-06-04 | | 公開日 | 2002-06-12 | | 最終更新日 | 2021-02-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of Escherichia coli uridine phosphorylase at 2.0 A.
Acta Crystallogr.,Sect.D, 59, 2003
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4YNH
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1LWS
 | | Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence | | 分子名称: | CALCIUM ION, ENDONUCLEASE PI-SCEI, PI-SceI DNA recognition region bottom strand, ... | | 著者 | Moure, C.M, Gimble, F.S, Quiocho, F.A. | | 登録日 | 2002-06-03 | | 公開日 | 2002-09-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence.
Nat.Struct.Biol., 9, 2002
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4YCQ
 | | Beta1 synthetic solenoid protein | | 分子名称: | beta1 protein | | 著者 | Murray, J.W. | | 登録日 | 2015-02-20 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | | 主引用文献 | Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1LXN
 | | X-RAY STRUCTURE OF MTH1187 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT272 | | 分子名称: | HYPOTHETICAL PROTEIN MTH1187, SULFATE ION | | 著者 | Tao, X, Khayat, R, Christendat, D, Savchenko, A, Xu, X, Edwards, A, Arrowsmith, C.H, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2002-06-05 | | 公開日 | 2003-07-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of MTH1187 and its Yeast Ortholog YBL001C
Proteins, 52, 2003
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4YNQ
 | | TREX1-dsDNA complex | | 分子名称: | DNA (24-MER), DNA (5'-D(P*GP*TP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*AP*CP*GP*AP*CP*G)-3'), MAGNESIUM ION, ... | | 著者 | Fye, J.M, Harvey, S, Perrino, F.W, Hollis, T. | | 登録日 | 2015-03-10 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1LXE
 | | CRYSTAL STRUCTURE OF THE CATHELICIDIN MOTIF OF PROTEGRINS | | 分子名称: | protegrin-3 precursor | | 著者 | Sanchez, J.F, Hoh, F, Strub, M.P, Aumelas, A, Dumas, C. | | 登録日 | 2002-06-05 | | 公開日 | 2002-10-09 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the cathelicidin motif of protegrin-3 precursor: structural insights into the activation mechanism of an antimicrobial protein.
Structure, 10, 2002
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4YCX
 | | Binary complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate | | 分子名称: | DNA (5'-D(*CP*GP*GP*CP*AP*AP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), DNA (5'-D(P*GP*CP*CP*G)-3'), ... | | 著者 | Moon, A.F, Gosavi, R.A, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | | 登録日 | 2015-02-20 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Creative template-dependent synthesis by human polymerase mu.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1LYD
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4YO7
 | | Crystal Structure of an ABC transporter solute binding protein (IPR025997) from Bacillus halodurans C-125 (BH2323, TARGET EFI-511484) with bound myo-inositol | | 分子名称: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Yadava, U, Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Koss, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2015-03-11 | | 公開日 | 2015-03-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of an ABC transporter solute binding protein (IPR025997) from Bacillus halodurans C-125 (BH2323, TARGET EFI-511484) with bound myo-inositol
To be published
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1LY4
 | | Analysis of quinazoline and PYRIDO[2,3D]PYRIMIDINE N9-C10 reversed bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase | | 分子名称: | 2,4-DIAMINO-6-[N-(3',5'-DIMETHOXYBENZYL)-N-METHYLAMINO]PYRIDO[2,3-D]PYRIMIDINE, DIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Queener, S.F, Gangjee, A. | | 登録日 | 2002-06-06 | | 公開日 | 2002-08-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase.
Acta Crystallogr.,Sect.D, 58, 2002
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4YOG
 | | HKU4-3CLpro bound to non-covalent inhibitor 3B | | 分子名称: | 3C-like proteinase, ACETATE ION, N-[4-(acetylamino)phenyl]-2-(1H-benzotriazol-1-yl)-N-[(1R)-2-(tert-butylamino)-2-oxo-1-(thiophen-3-yl)ethyl]acetamide | | 著者 | St John, S.E, Mesecar, A. | | 登録日 | 2015-03-11 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4-The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS).
Bioorg.Med.Chem., 23, 2015
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1LYH
 | | DISSECTION OF HELIX CAPPING IN T4 LYSOZYME BY STRUCTURAL AND THERMODYNAMIC ANALYSIS OF SIX AMINO ACID SUBSTITUTIONS AT THR 59 | | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | | 著者 | Bell, J.A, Becktel, W.J, Sauer, U, Baase, W.A, Matthews, B.W. | | 登録日 | 1992-08-10 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Dissection of helix capping in T4 lysozyme by structural and thermodynamic analysis of six amino acid substitutions at Thr 59.
Biochemistry, 31, 1992
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1LYA
 | | CRYSTAL STRUCTURES OF NATIVE AND INHIBITED FORMS OF HUMAN CATHEPSIN D: IMPLICATIONS FOR LYSOSOMAL TARGETING AND DRUG DESIGN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CATHEPSIN D, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Baldwin, E.T, Bhat, T.N, Gulnik, S, Erickson, J.W. | | 登録日 | 1993-04-22 | | 公開日 | 1994-01-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.
Proc.Natl.Acad.Sci.USA, 90, 1993
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4YD7
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4YOQ
 | | Crystal Structure of MutY bound to its anti-substrate | | 分子名称: | A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*T*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ... | | 著者 | Wang, L, Lee, S, Verdine, G.L. | | 登録日 | 2015-03-11 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
J.Biol.Chem., 290, 2015
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1LYY
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4YDN
 | | High resolution crystal structure of human transthyretin bound to ligand and conjugates of 4-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)phenyl fluorosulfate | | 分子名称: | 2,6-dichloro-4-[5-(4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]phenol, 4-[5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]phenyl sulfurofluoridate, Transthyretin | | 著者 | Connelly, S, Bradbury, N.C. | | 登録日 | 2015-02-22 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans.
J.Am.Chem.Soc., 137, 2015
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