4YOQ

Crystal Structure of MutY bound to its anti-substrate

Summary for 4YOQ

• Entry DOI: 10.2210/pdb4yoq/pdb
• Related: 4YPH 4YPR
• Descriptor: A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*T*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ... (7 entities in total)
• Functional Keywords: 8-oxoguanine, base-excision repair, anti-substrate, hydrolase-dna complex, hydrolase/dna
• Biological source: Geobacillus stearothermophilus; More
• Total number of polymer chains: 3
• Total formula weight: 49289.06

Authors

Wang, L.,Lee, S.,Verdine, G.L. (deposition date: 2015-03-11, release date: 2015-05-27, Last modification date: 2023-09-27)

• Primary citation: Wang, L.,Lee, S.J.,Verdine, G.L.; Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.; J.Biol.Chem., 290:17096-17105, 2015; PubMed: 25995449; DOI: 10.1074/jbc.M115.657866

Experimental method

X-RAY DIFFRACTION (2.21 Å)