4YOQ
Crystal Structure of MutY bound to its anti-substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | A/G-specific adenine glycosylase | polymer | 369 | 42098.9 | 1 | UniProt (P83847) Pfam (PF00730) Pfam (PF00633) Pfam (PF10576) Pfam (PF14815) | Geobacillus stearothermophilus | |
| 2 | B (B) | DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3') | polymer | 11 | 3423.2 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (5'-D(*T*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3') | polymer | 11 | 3300.2 | 1 | synthetic construct | ||
| 4 | D (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 5 | E (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | G, H, I (A, B, C) | water | water | 18.0 | 127 | Chemie (HOH) |
Sequence modifications
A: 1 - 366 (UniProt: P83847)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Asp 144 | Asn 144 | engineered mutation |
| Cys 164 | Pro 164 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 48822.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 466.7 | |
| All* | Total formula weight | 49289.1 |
