1LWS
 
 | | Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence | | Descriptor: | CALCIUM ION, ENDONUCLEASE PI-SCEI, PI-SceI DNA recognition region bottom strand, ... | | Authors: | Moure, C.M, Gimble, F.S, Quiocho, F.A. | | Deposit date: | 2002-06-03 | | Release date: | 2002-09-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence.
Nat.Struct.Biol., 9, 2002
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1LWT
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6X1J
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3OOR
 | | I-SceI mutant (K86R/G100T)complexed with C/G+4 DNA substrate | | Descriptor: | 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', CALCIUM ION, ... | | Authors: | Joshi, R, Chen, J.-H, Golden, B.L, Gimble, F.S. | | Deposit date: | 2010-08-31 | | Release date: | 2010-11-17 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity.
J.Mol.Biol., 405, 2011
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3OOL
 | | I-SceI complexed with C/G+4 DNA substrate | | Descriptor: | 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', CALCIUM ION, ... | | Authors: | Joshi, R, Chen, J.-H, Golden, B.L, Gimble, F.S. | | Deposit date: | 2010-08-31 | | Release date: | 2010-11-17 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity.
J.Mol.Biol., 405, 2011
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1R7M
 | | The homing endonuclease I-SceI bound to its DNA recognition region | | Descriptor: | 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*AP*GP*GP*GP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*GP*TP*AP*TP*TP*AP*CP*CP*CP*TP*GP*TP*TP*AP*TP*CP*CP*CP*TP*AP*GP*CP*GP*T)-3', CALCIUM ION, ... | | Authors: | Moure, C.M, Gimble, F.S, Quiocho, F.A. | | Deposit date: | 2003-10-21 | | Release date: | 2004-10-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity
J.Mol.Biol., 334, 2003
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1DFA
 | | CRYSTAL STRUCTURE OF PI-SCEI IN C2 SPACE GROUP | | Descriptor: | PI-SCEI ENDONUCLEASE | | Authors: | Hu, D, Crist, M, Duan, X, Quiocho, F.A, Gimble, F.S. | | Deposit date: | 1999-11-18 | | Release date: | 1999-12-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Probing the structure of the PI-SceI-DNA complex by affinity cleavage and affinity photocross-linking.
J.Biol.Chem., 275, 2000
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3C0X
 | | I-SceI in complex with a top nicked DNA substrate | | Descriptor: | CALCIUM ION, DNA (5'-D(*DC*DAP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DGP*DAP*DTP*DAP*DA)-3'), DNA (5'-D(*DG*DGP*DTP*DAP*DTP*DTP*DAP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DTP*DCP*DCP*DCP*DTP*DAP*DGP*DCP*DGP*DT)-3'), ... | | Authors: | Moure, C.M, Gimble, F.S, Quiocho, F.A. | | Deposit date: | 2008-01-21 | | Release date: | 2008-05-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway.
Nucleic Acids Res., 36, 2008
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3C0W
 | | I-SceI in complex with a bottom nicked DNA substrate | | Descriptor: | CALCIUM ION, DNA (5'-D(*DAP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DGP*DAP*DTP*DAP*DAP*DCP*DAP*DGP*DGP*DGP*DTP*DAP*DAP*DTP*DAP*DC)-3'), DNA (5'-D(*DGP*DTP*DAP*DTP*DTP*DAP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DT)-3'), ... | | Authors: | Moure, C.M, Gimble, F.S, Quiocho, F.A. | | Deposit date: | 2008-01-21 | | Release date: | 2008-05-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway.
Nucleic Acids Res., 36, 2008
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