Structure of human DNA polymerase beta complexed with N7BG in the template base paired with incoming non-hydrolyzable CTP

Summary for 4YMN

Related4YMM 4YMO 4YN4
DescriptorDNA polymerase beta, DNA 16-mer (template), DNA 10-mer (up-primer), ... (8 entities in total)
Functional Keywordshuman dna polymerase beta, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total molecular weight48352.46
Lee, S.,Koag, M.-C. (deposition date: 2015-03-06, release date: 2016-03-09, Last modification date: 2018-07-25)
Primary citation
Kou, Y.,Koag, M.C.,Lee, S.
Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication.
Biochemistry, 2018
PubMed: 29957995 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.8b00331
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26690 2.5% 7.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-10-14