4YMO
Structure of human DNA polymerase beta complexed with N7BG in the template opposite to incoming non-hydrolyzable CTP WITH MANGANESE IN THE ACTIVE SITE
Summary for 4YMO
Entry DOI | 10.2210/pdb4ymo/pdb |
Related | 4YMM 4YMN 4YN4 |
Descriptor | DNA polymerase beta, DNA 16-mer (template), DNA 10-mer (up-primer), ... (8 entities in total) |
Functional Keywords | human dna polymerase beta, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 48438.03 |
Authors | Lee, S.,Koag, M.-C. (deposition date: 2015-03-07, release date: 2016-03-09, Last modification date: 2024-02-28) |
Primary citation | Kou, Y.,Koag, M.C.,Lee, S. Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication. Biochemistry, 2018 Cited by PubMed: 29957995DOI: 10.1021/acs.biochem.8b00331 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.148 Å) |
Structure validation
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