PDB: 7742 件ウェブページステータス検索Chemie searchBIRD

---

5YPT	Crystal structure of Marchantia paleacea chalone synthase like 1 (CHSL1) 分子名称: Stilbenecarboxylate synthase 1 著者 Lou, H.X, Yu, H. 登録日 2017-11-03 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.394 Å) 主引用文献 Structural and biochemical characterization of the plant type III polyketide synthases of the liverwort Marchantia paleacea. Plant Physiol. Biochem., 125, 2018
5WOT	NMR solution structure of a-lytic protease using two 4D-spectra 分子名称: Alpha-lytic protease 著者 Evangelidis, T, Nerli, S, Sgourakis, N.G, Tripsianes, K. 登録日 2017-08-03 公開日 2018-02-07 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra. Nat Commun, 9, 2018
6AN6	Crystal structure of Escherichia coli HPPK in complex with bisubstrate analogue inhibitor HP-72 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 5'-S-{2-[{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}(phosphonomethyl)amino]ethyl}-5'-thioadenosine 著者 Shaw, G.X, Shi, G, Ji, X. 登録日 2017-08-12 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Bisubstrate analogue inhibitors of HPPK: Transition state mimetics to be published
5JO0	Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC56 and manganese 分子名称: 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, ... 著者 Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. 登録日 2016-05-01 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin. Chemmedchem, 11, 2016
5JBI	Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC52 and manganese 分子名称: 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, ... 著者 Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. 登録日 2016-04-13 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin. Chemmedchem, 11, 2016
5JNL	Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC54 and manganese 分子名称: 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, ... 著者 Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. 登録日 2016-04-30 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin. Chemmedchem, 11, 2016
5JAZ	Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC51 and manganese 分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, FORMIC ACID, ... 著者 Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. 登録日 2016-04-12 公開日 2016-08-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin. Chemmedchem, 11, 2016
5JMP	Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC57 and manganese 分子名称: 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, ... 著者 Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. 登録日 2016-04-29 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin. Chemmedchem, 11, 2016
5UE2	proMMP-7 with heparin octasaccharide bridging between domains 分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, Matrilysin, ... 著者 Fulcher, Y.G, Prior, S.H, Linhardt, R.J, Van Doren, S.R. 登録日 2016-12-29 公開日 2017-07-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Glycan Activation of a Sheddase: Electrostatic Recognition between Heparin and proMMP-7. Structure, 25, 2017
6G1O	Structure of Pseudomonas aeruginosa Isocitrate Lyase, ICL 分子名称: CALCIUM ION, GLYOXYLIC ACID, Isocitrate lyase 著者 Crousilles, A, Welch, M. 登録日 2018-03-21 公開日 2018-08-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.882 Å) 主引用文献 Gluconeogenic precursor availability regulates flux through the glyoxylate shunt inPseudomonas aeruginosa. J. Biol. Chem., 293, 2018
4WLB	Crystal structure of RORc in complex with a partial inverse agonist compound 分子名称: L(+)-TARTARIC ACID, N-(4-fluorobenzyl)-N-(2-methylpropyl)-6-{[1-(methylsulfonyl)piperidin-4-yl]amino}pyridine-3-sulfonamide, Nuclear receptor ROR-gamma, ... 著者 Boenig, G, Hymowitz, S.G, Kiefer, J.R. 登録日 2014-10-07 公開日 2014-11-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 A reversed sulfonamide series of selective RORc inverse agonists. Bioorg.Med.Chem.Lett., 24, 2014
4WRN	Crystal structure of the polymerization region of human uromodulin/Tamm-Horsfall protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Maltose-binding periplasmic protein,Uromodulin, ZINC ION, ... 著者 Bokhove, M, De Sanctis, D, Jovine, L. 登録日 2014-10-24 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 A structured interdomain linker directs self-polymerization of human uromodulin. Proc.Natl.Acad.Sci.USA, 113, 2016
4YN4	Structure of human DNA polymerase beta complexed with N7BG in the template opposite to incoming non-hydrolyzable dTTP WITH MANGANESE IN THE ACTIVE SITE 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA 10-mer (up-primer), DNA 16-mer (template), ... 著者 Lee, S, Koag, M.-C. 登録日 2015-03-09 公開日 2016-03-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.243 Å) 主引用文献 Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication. Biochemistry, 2018
5JMW	Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC50 and manganese 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, ... 著者 Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. 登録日 2016-04-29 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin. Chemmedchem, 11, 2016
4YA8	structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor PG394 分子名称: GLYCEROL, N'-[(2S,3S)-3-hydroxy-1-phenyl-4-{[2-(pyridin-2-yl)propan-2-yl]amino}butan-2-yl]-N,N-dipropyl-5-(pyridin-1(2H)-yl)benzene-1,3-dicarboxamide, Plasmepsin-2 著者 Recacha, R, Leitans, J, Tars, K, Jaudzems, K. 登録日 2015-02-17 公開日 2015-12-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors. Acta Crystallogr.,Sect.F, 71, 2015
5L06	Solution Structure of a DNA Dodecamer with 5-methylcytosine at the 3rd Position 分子名称: DNA (5'-D(*CP*GP*(5CM)P*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') 著者 Miears, H.L, Hoppins, J.J, Gruber, D.R, Kasymov, R.D, Zharkov, D.O, Smirnov, S.L. 登録日 2016-07-26 公開日 2016-12-21 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation. Nucleic Acids Res., 46, 2018
4YMN	Structure of human DNA polymerase beta complexed with N7BG in the template base paired with incoming non-hydrolyzable CTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA 10-mer (up-primer), DNA 16-mer (template), ... 著者 Lee, S, Koag, M.-C. 登録日 2015-03-06 公開日 2016-03-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.591 Å) 主引用文献 Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication. Biochemistry, 2018
5JC1	Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC55 and manganese 分子名称: 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, ... 著者 Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. 登録日 2016-04-14 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin. Chemmedchem, 11, 2016
5L2G	Solution Structure of a DNA Dodecamer with 5-methylcytosine at the 9th Position 分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(5CM)P*GP*CP*G)-3') 著者 Miears, H.L, Hoppins, J.J, Gruber, D.R, Kasymov, R.D, Johnson, E.C, Zharkov, D.O, Smirnov, S.L. 登録日 2016-08-01 公開日 2016-12-21 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation. Nucleic Acids Res., 46, 2018
6AN4	Crystal structure of Escherichia coli HPPK in complex with bisubstrate analogue inhibitor HP-39 (J1F) 分子名称: ((2-(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carboxamido)-N-(2-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)amino)-2-oxoethyl)acetamido)methyl)phosphonic acid, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION 著者 Shaw, G.X, Shi, G, Ji, X. 登録日 2017-08-12 公開日 2018-08-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Bisubstrate analog inhibitors of HPPK: Transition state mimetics to be published
4YMM	Structure of human DNA polymerase beta complexed with 7BG as the template base in a 1-nucleotide gapped DNA 分子名称: DNA 10-mer (up-primer), DNA 16-mer (template), DNA 5-mer (dn-primer), ... 著者 Lee, S, Koag, M.-C. 登録日 2015-03-06 公開日 2016-03-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Structure of human DNA polymerase beta complexed with 7BG as the template base in a 1-nucleotide gapped DNA To Be Published
4Z22	structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor DR718A 分子名称: 2-amino-7-phenyl-3-{[(2R,5S)-5-phenyltetrahydrofuran-2-yl]methyl}quinazolin-4(3H)-one, Plasmepsin-2 著者 Recacha, R, Leitans, J, Tars, K, Jaudzems, K. 登録日 2015-03-28 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV. J.Med.Chem., 59, 2016
7XO0	Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient 分子名称: Alpha-synuclein 著者 Fan, Y, Sun, Y.P, Wang, J, Liu, C. 登録日 2022-04-30 公開日 2022-11-30 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease. Structure, 31, 2023
6GWV	Molybdenum storage protein without polymolybdate clusters and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Molybdenum storage protein subunit alpha, ... 著者 Ermler, U, Poppe, J, Bruenle, S. 登録日 2018-06-26 公開日 2018-11-07 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Molybdenum Storage Protein: A soluble ATP hydrolysis-dependent molybdate pump. FEBS J., 285, 2018
7KDO	Crystal structure of Escherichia coli HPPK in complex with bisubstrate inhibitor HP-73 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 5'-S-[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]-5'-thioadenosine 著者 Shaw, G.X, Shi, G, Ji, X. 登録日 2020-10-09 公開日 2020-12-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding. Bioorg.Med.Chem., 29, 2021

<77787980818283848586878889909192>