4WRN
Crystal structure of the polymerization region of human uromodulin/Tamm-Horsfall protein
Summary for 4WRN
| Entry DOI | 10.2210/pdb4wrn/pdb |
| Related | 3D4G 3NK4 5BUP |
| Related PRD ID | PRD_900001 |
| Descriptor | Maltose-binding periplasmic protein,Uromodulin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
| Functional Keywords | zp domain, egf domain, extracellular matrix, glycoprotein, structural protein |
| Biological source | Escherichia coli O157:H7 More |
| Total number of polymer chains | 2 |
| Total formula weight | 154557.86 |
| Authors | Bokhove, M.,De Sanctis, D.,Jovine, L. (deposition date: 2014-10-24, release date: 2016-01-27, Last modification date: 2024-01-10) |
| Primary citation | Bokhove, M.,Nishimura, K.,Brunati, M.,Han, L.,de Sanctis, D.,Rampoldi, L.,Jovine, L. A structured interdomain linker directs self-polymerization of human uromodulin. Proc.Natl.Acad.Sci.USA, 113:1552-1557, 2016 Cited by PubMed: 26811476DOI: 10.1073/pnas.1519803113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
Download full validation report
