PDB: 2956 件ウェブページステータス検索Chemie searchBIRD

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6BIY	HLA-DRB1 in complex with Histone 2B peptide 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II DR-beta (HLA-DR B), ... 著者 Ting, Y.T, Scally, S.W, Rossjohn, J. 登録日 2017-11-03 公開日 2018-01-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.050049 Å) 主引用文献 The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. J. Biol. Chem., 293, 2018
6BKC	Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3B 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab AR3B heavy chain, Fab AR3B light chain, ... 著者 Tzarum, N, Wilson, I.A, Law, M. 登録日 2017-11-08 公開日 2018-12-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies. Sci Adv, 5, 2019
6BGT	Structure of Trastuzumab Fab mutant in complex with Her2 extracellular domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Herceptin heavy chain Fab fragment mutant, Herceptin light chain mutant, ... 著者 Christie, M, Christ, D. 登録日 2017-10-29 公開日 2018-10-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Stable human IgG antibody therapeutics with native framework structure To Be Published
6BIR	HLA-DRB1 in complex with citrullinated Vimentin peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... 著者 Ting, Y.T, Scally, S.W, Rossjohn, J. 登録日 2017-11-02 公開日 2018-01-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. J. Biol. Chem., 293, 2018
4HIX	Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide 分子名称: Beta-amyloid protein 40, Humanized 3D6 Fab heavy chain, Humanized 3D6 Fab light chain 著者 Miles, L.A, Crespi, G.A.N, Parker, M.W. 登録日 2012-10-12 公開日 2013-03-13 最終更新日 2014-03-19 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation. Sci Rep, 3, 2013
4HKJ	Structure of Cowpox CPXV203 in complex with MHCI (H-2Kb) 分子名称: Beta-2-microglobulin, CPXV203 protein, H-2 class I histocompatibility antigen, ... 著者 McCoy IV, W.H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-10-15 公開日 2012-11-14 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Mechanism of ER Retrieval of MHC Class I by Cowpox. Plos Biol., 10, 2012
4HUV	Crystal Structure of H2Db-NPM6W 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... 著者 Gras, S, Twist, K.A, Rossjohn, J. 登録日 2012-11-04 公開日 2013-02-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Preemptive priming readily overcomes structure-based mechanisms of virus escape. Proc.Natl.Acad.Sci.USA, 110, 2013
4HUW	Crystal Structure of H2Db-NPM6T 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... 著者 Gras, S, Twist, K.A, Rossjohn, J. 登録日 2012-11-04 公開日 2013-02-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 Preemptive priming readily overcomes structure-based mechanisms of virus escape. Proc.Natl.Acad.Sci.USA, 110, 2013
4I0P	HLA-DO in complex with HLA-DM 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GLYCEROL, ... 著者 Guce, A.I, Mortimer, S.E, Stern, L.J. 登録日 2012-11-18 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism. Nat.Struct.Mol.Biol., 20, 2013
4HUX	Crystal Structure of H2Db-H155A-NP 分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ... 著者 Gras, S, Twist, K.A, Rossjohn, J. 登録日 2012-11-05 公開日 2013-02-27 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Preemptive priming readily overcomes structure-based mechanisms of virus escape. Proc.Natl.Acad.Sci.USA, 110, 2013
4HX1	Structure of HLA-A68 complexed with a tumor antigen derived peptide 分子名称: 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ... 著者 Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. 登録日 2012-11-09 公開日 2013-10-02 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
4HS3	Crystal structure of H-2Kb with a disulfide stabilized F pocket in complex with the LCMV derived peptide GP34 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-2-microglobulin, Envelope glycoprotein, ... 著者 Uchtenhagen, H, Boulanger, B, Hein, Z, Abualrous, E.T, Zacharias, M, Werner, J, Elliott, T, Springer, S, Achour, A. 登録日 2012-10-29 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Peptide-independent stabilization of MHC class I molecules breaches cellular quality control. J.Cell.Sci., 127, 2014
4I4W	Peptide length determines the outcome of T cell receptor/peptide-MHCI engagement 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... 著者 Rizkallah, P.J, Wooldridge, L, Cole, D.K. 登録日 2012-11-28 公開日 2013-01-02 最終更新日 2015-11-25 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood, 121, 2013
4JQX	HLA-B*44:03 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 169-180) 分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ... 著者 Theodossis, A, Welland, A, Gras, S, Rossjohn, J. 登録日 2013-03-20 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 HLA Peptide Length Preferences Control CD8+ T Cell Responses. J.Immunol., 191, 2013
4JFE	Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
4JFO	A2 HLA complex with E1A heteroclitic variant of Melanoma peptide 分子名称: Beta-2-microglobulin, E1A heteroclitic Melanoma peptide, GLYCEROL, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K, Baker, B.M. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
4JFD	Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
4JFP	A2 HLA complex with G4A heteroclitic variant of Melanoma peptide 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
4JRY	Crystal Structure of SB47 TCR-HLA B*3505-LPEP complex 分子名称: Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ... 著者 Liu, Y.C, Rossjohn, J, Gras, S. 登録日 2013-03-22 公開日 2013-04-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule. J.Biol.Chem., 288, 2013
4JFF	Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2014-04-02 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
4H25	TCR interaction with peptide mimics of nickel offers structure insights to nickel contact allergy 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... 著者 Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F. 登録日 2012-09-12 公開日 2013-10-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
4KK5	Structure of the CLC-ec1 deltaNC construct in 20mM fluoride and 20mM bromide 分子名称: Fab, heavy chain, light chain, ... 著者 Lim, H.-H, Miller, C. 登録日 2013-05-05 公開日 2013-08-21 最終更新日 2013-11-13 実験手法 X-RAY DIFFRACTION (3.171 Å) 主引用文献 Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4KK8	Structure of the E148Q mutant of CLC-ec1 deltaNC construct in 100mM fluoride 分子名称: FLUORIDE ION, Fab, heavy chain, ... 著者 Lim, H.-H, Miller, C. 登録日 2013-05-05 公開日 2013-08-21 最終更新日 2013-11-13 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter. Nat.Chem.Biol., 9, 2013
4HWZ	Structure of HLA-A68 complexed with an HIV derived peptide 分子名称: 9-mer peptide from Pol protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. 登録日 2012-11-09 公開日 2013-10-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.397 Å) 主引用文献 Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
4I5B	Structure of human MHC class II protein HLA-DR1 carrying an influenza hemagglutinin peptide partially filling the binding groove 分子名称: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... 著者 Schulze, M.-S.E.D. 登録日 2012-11-28 公開日 2013-12-04 最終更新日 2015-04-15 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Disruption of hydrogen bonds between major histocompatibility complex class II and the peptide N-terminus is not sufficient to form a human leukocyte antigen-DM receptive state of major histocompatibility complex class II. Plos One, 8, 2013

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