4I4W
Peptide length determines the outcome of T cell receptor/peptide-MHCI engagement
Summary for 4I4W
Entry DOI | 10.2210/pdb4i4w/pdb |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Immunogenic peptide, ... (7 entities in total) |
Functional Keywords | mhc i fold, antigen presentation, t-cell receptor, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted : P61769 |
Total number of polymer chains | 3 |
Total formula weight | 46529.72 |
Authors | Rizkallah, P.J.,Wooldridge, L.,Cole, D.K. (deposition date: 2012-11-28, release date: 2013-01-02, Last modification date: 2015-11-25) |
Primary citation | Ekeruche-Makinde, J.,Miles, J.J.,van den Berg, H.A.,Skowera, A.,Cole, D.K.,Dolton, G.,Schauenburg, A.J.,Tan, M.P.,Pentier, J.M.,Llewellyn-Lacey, S.,Miles, K.M.,Bulek, A.M.,Clement, M.,Williams, T.,Trimby, A.,Bailey, M.,Rizkallah, P.J.,Rossjohn, J.,Peakman, M.,Price, D.A.,Burrows, S.R.,Sewell, A.K.,Wooldridge, L. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood, 121:1112-1123, 2013 Cited by PubMed: 23255554DOI: 10.1182/blood-2012-06-437202 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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