4HUW

Crystal Structure of H2Db-NPM6T

Summary for 4HUW

• Entry DOI: 10.2210/pdb4huw/pdb
• Related: 1hoc 3cpl 4HUU 4HUV 4HUX 4HV8
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, NPM6T variant peptide, ... (5 entities in total)
• Functional Keywords: viral immunity, t cell, h2db, influenza, viral escape, immune system
• Biological source: Mus musculus (mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887
• Total number of polymer chains: 12
• Total formula weight: 182035.74

Authors

Gras, S.,Twist, K.A.,Rossjohn, J. (deposition date: 2012-11-04, release date: 2013-02-27, Last modification date: 2023-09-20)

• Primary citation: Valkenburg, S.A.,Gras, S.,Guillonneau, C.,Hatton, L.A.,Bird, N.A.,Twist, K.A.,Halim, H.,Jackson, D.C.,Purcell, A.W.,Turner, S.J.,Doherty, P.C.,Rossjohn, J.,Kedzierska, K.; Preemptive priming readily overcomes structure-based mechanisms of virus escape.; Proc.Natl.Acad.Sci.USA, 110:5570-5575, 2013; PubMed: 23493558; DOI: 10.1073/pnas.1302935110

Experimental method

X-RAY DIFFRACTION (3.16 Å)