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4HV8

Crystal Structure of H2Db-H155A-NPM6I

Summary for 4HV8
Entry DOI10.2210/pdb4hv8/pdb
Related1hoc 3cpl 4HUU 4HUV 4HUW 4HUX
DescriptorH-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, NPM6I variant peptide, ... (5 entities in total)
Functional Keywordsviral immunity, t cell, h2db, influenza, viral escape, immune system
Biological sourceMus musculus (mouse)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01899
Secreted: P01887
Total number of polymer chains6
Total formula weight91244.06
Authors
Gras, S.,Twist, K.A.,Rossjohn, J. (deposition date: 2012-11-05, release date: 2013-02-27, Last modification date: 2023-09-20)
Primary citationValkenburg, S.A.,Gras, S.,Guillonneau, C.,Hatton, L.A.,Bird, N.A.,Twist, K.A.,Halim, H.,Jackson, D.C.,Purcell, A.W.,Turner, S.J.,Doherty, P.C.,Rossjohn, J.,Kedzierska, K.
Preemptive priming readily overcomes structure-based mechanisms of virus escape.
Proc.Natl.Acad.Sci.USA, 110:5570-5575, 2013
Cited by
PubMed: 23493558
DOI: 10.1073/pnas.1302935110
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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