4H25

TCR interaction with peptide mimics of nickel offers structure insights to nickel contact allergy

Summary for 4H25

• Entry DOI: 10.2210/pdb4h25/pdb
• Related: 4H1L 4H26
• Descriptor: HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen, peptide, ... (6 entities in total)
• Functional Keywords: protein protein complex, immunoglobulin fold, antigen presentation, tcr, cell surface, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 93467.08

Authors

Kappler, J.W.,Yin, L.,Dai, S.,Marrack, P.,Crawford, F. (deposition date: 2012-09-12, release date: 2013-10-16, Last modification date: 2024-04-03)

• Primary citation: Yin, L.,Crawford, F.,Marrack, P.,Kappler, J.W.,Dai, S.; T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.; Proc.Natl.Acad.Sci.USA, 109:18517-18522, 2012; PubMed: 23091041; DOI: 10.1073/pnas.1215928109

Experimental method

X-RAY DIFFRACTION (2.2 Å)