4HS3

Crystal structure of H-2Kb with a disulfide stabilized F pocket in complex with the LCMV derived peptide GP34

Summary for 4HS3

Entry DOI	10.2210/pdb4hs3/pdb
Descriptor	H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, Envelope glycoprotein, ... (6 entities in total)
Functional Keywords	mhc class i, antigen presentation, antigen processing, peptide binding, igg, mhc, immune system
Biological source	Mus musculus (mouse) More
Cellular location	Membrane; Single-pass type I membrane protein: P01901 Secreted: P01887
Total number of polymer chains	3
Total formula weight	44680.14
Authors	Uchtenhagen, H.,Boulanger, B.,Hein, Z.,Abualrous, E.T.,Zacharias, M.,Werner, J.,Elliott, T.,Springer, S.,Achour, A. (deposition date: 2012-10-29, release date: 2014-05-07, Last modification date: 2023-09-20)
Primary citation	Hein, Z.,Uchtenhagen, H.,Abualrous, E.T.,Saini, S.K.,Janen, L.,Van Hateren, A.,Wiek, C.,Hanenberg, H.,Momburg, F.,Achour, A.,Elliott, T.,Springer, S.,Boulanger, D. Peptide-independent stabilization of MHC class I molecules breaches cellular quality control. J.Cell.Sci., 127:2885-2897, 2014 Cited by PubMed: 24806963 DOI: 10.1242/jcs.145334 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation