4HS3

Crystal structure of H-2Kb with a disulfide stabilized F pocket in complex with the LCMV derived peptide GP34

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	H-2 class I histocompatibility antigen, K-B alpha chain	polymer	276	31846.6	1	UniProt (P01901) Pfam (PF00129) Pfam (PF07654) In PDB	Mus musculus (mouse)	H-2K(B)
2	B	Beta-2-microglobulin	polymer	99	11704.4	1	UniProt (P01887) Pfam (PF07654) In PDB	Mus musculus (mouse)
3	C	Envelope glycoprotein	polymer	8	916.1	1	UniProt (Q9WKU1) In PDB	Lymphocytic choriomeningitis virus
4	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	B	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	1	Chemie (MPD)
6		water	water		18.0	418	Chemie (HOH)

Sequence modifications

A: 1 - 276 (UniProt: P01901)

PDB	External Database	Details
Cys 84	Tyr 105	engineered mutation
Cys 139	Ala 160	engineered mutation

B: 1 - 99 (UniProt: P01887)

PDB	External Database	Details
Asp 85	Ala 105	variant

C: 1 - 8 (UniProt: Q9WKU1)

PDB	External Database	Details
Met 8	Cys 41	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	44467.0
Non-Polymers*	Number of molecules	2
	Total formula weight	213.1
All*	Total formula weight	44680.1

*Water molecules are not included.