4HS3
Crystal structure of H-2Kb with a disulfide stabilized F pocket in complex with the LCMV derived peptide GP34
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | H-2 class I histocompatibility antigen, K-B alpha chain | polymer | 276 | 31846.6 | 1 | UniProt (P01901) Pfam (PF00129) Pfam (PF07654) | Mus musculus (mouse) | H-2K(B) |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11704.4 | 1 | UniProt (P01887) Pfam (PF07654) | Mus musculus (mouse) | |
| 3 | C (C) | Envelope glycoprotein | polymer | 8 | 916.1 | 1 | UniProt (Q9WKU1) | Lymphocytic choriomeningitis virus | |
| 4 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | E (B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 6 | F, G, H (A, B, C) | water | water | 18.0 | 418 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: P01901)
B: 1 - 99 (UniProt: P01887)
C: 1 - 8 (UniProt: Q9WKU1)
| PDB | External Database | Details |
|---|---|---|
| Cys 84 | Tyr 105 | engineered mutation |
| Cys 139 | Ala 160 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Asp 85 | Ala 105 | variant |
| PDB | External Database | Details |
|---|---|---|
| Met 8 | Cys 41 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44467.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 213.1 | |
| All* | Total formula weight | 44680.1 |
