8PKI
| Cryo-EM structure of NR5A2-nucleosome complex SHL+5.5 | 分子名称: | DNA, Histone H2A, Histone H2B type 1-C/E/G, ... | 著者 | Kobayashi, W, Sappler, A, Bollschweiler, D, Kummecke, M, Basquin, J, Arslantas, E, Ruangroengkulrith, S, Hornberger, R, Duderstadt, K, Tachibana, K. | 登録日 | 2023-06-26 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition. Nat.Struct.Mol.Biol., 31, 2024
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8BXY
| FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group | 分子名称: | NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ... | 著者 | Bridot, C, Bouckaert, J, Krammer, E.-M. | 登録日 | 2022-12-11 | 公開日 | 2023-04-12 | 最終更新日 | 2023-04-26 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors. J.Biol.Chem., 299, 2023
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2NU7
| C123aS Mutant of E. coli Succinyl-CoA Synthetase | 分子名称: | COENZYME A, PHOSPHATE ION, SULFATE ION, ... | 著者 | Fraser, M.E. | 登録日 | 2006-11-08 | 公開日 | 2007-07-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Participation of Cys 123alpha of Escherichia coli Succinyl-CoA Synthetase in Catalysis ACTA CRYSTALLOGR.,SECT.D, 63, 2007
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6HCK
| The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with dipeptide Leu-Leu | 分子名称: | LEUCINE, Listeriolysin regulatory protein, SODIUM ION | 著者 | Grundstrom, C, Oelker, M, Krypotou, E, Scortti, M, Luisi, B.F, Vazquez-Boland, J, Sauer-Eriksson, A.E. | 登録日 | 2018-08-15 | 公開日 | 2019-02-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Control of Bacterial Virulence through the Peptide Signature of the Habitat. Cell Rep, 26, 2019
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7TIT
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7TJ7
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7TIJ
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6UXM
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8BY6
| Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and cap-analogue m7GpppG | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... | 著者 | Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. | 登録日 | 2022-12-12 | 公開日 | 2024-01-24 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
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9BRB
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9BRD
| Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3 | 分子名称: | (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Coupland, C.E, Rubinstein, J.L. | 登録日 | 2024-05-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | High-resolution electron cryomicroscopy of V-ATPase in native synaptic vesicles. Science, 385, 2024
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9BRC
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8PZB
| crystal structure of VDR in complex with D-Bishomo-1a,25-dihydroxyvitamin D3 Analog 49 | 分子名称: | (1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(4~{a}~{R},5~{S},9~{a}~{S})-4~{a}-methyl-5-[(2~{R})-6-methyl-6-oxidanyl-heptan-2-yl]-3,4,5,6,7,8,9,9~{a}-octahydro-2~{H}-benzo[7]annulen-1-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, Nuclear receptor coactivator 2, Vitamin D3 receptor A | 著者 | Rochel, N. | 登録日 | 2023-07-27 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Design, synthesis, and biological activity of D-bishomo-1 alpha ,25-dihydroxyvitamin D 3 analogs and their crystal structures with the vitamin D nuclear receptor. Eur.J.Med.Chem., 271, 2024
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8PZ7
| crystal structure of VDR complex with D-Bishomo-1a,25-dihydroxyvitamin D3 Analog 57 | 分子名称: | (1~{R},3~{R})-5-[(2~{E})-2-[(4~{a}~{R},5~{R},9~{a}~{S})-4~{a}-methyl-5-[(2~{R})-6-methyl-6-oxidanyl-heptan-2-yl]-3,4,5,8,9,9~{a}-hexahydro-2~{H}-benzo[7]annulen-1-ylidene]ethylidene]-2-methyl-cyclohexane-1,3-diol, Nuclear receptor coactivator 2, Vitamin D3 receptor A | 著者 | Rochel, N. | 登録日 | 2023-07-27 | 公開日 | 2023-08-30 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Design, synthesis, and biological activity of D-bishomo-1 alpha ,25-dihydroxyvitamin D 3 analogs and their crystal structures with the vitamin D nuclear receptor. Eur.J.Med.Chem., 271, 2024
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8PZ9
| Crystal structure of VDR in complex with D-Bishomo-1a,25-dihydroxyvitamin D3 Analog 55 | 分子名称: | (1~{R},3~{R})-5-[(2~{E})-2-[(4~{a}~{R},5~{R},9~{a}~{S})-4~{a}-methyl-5-[(2~{R})-6-methyl-6-oxidanyl-heptan-2-yl]-3,4,5,8,9,9~{a}-hexahydro-2~{H}-benzo[7]annulen-1-ylidene]ethylidene]-2-methylidene-cyclohexane-1,3-diol, Nuclear receptor coactivator 2, Vitamin D3 receptor A | 著者 | Rochel, N. | 登録日 | 2023-07-27 | 公開日 | 2023-08-30 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Design, synthesis, and biological activity of D-bishomo-1 alpha ,25-dihydroxyvitamin D 3 analogs and their crystal structures with the vitamin D nuclear receptor. Eur.J.Med.Chem., 271, 2024
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7B9V
| Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound | 分子名称: | 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ... | 著者 | Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K. | 登録日 | 2020-12-14 | 公開日 | 2021-03-10 | 最終更新日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for conformational equilibrium of the catalytic spliceosome. Mol.Cell, 81, 2021
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6J31
| Crystal Structure Analysis of the Glycotransferase of kitacinnamycin | 分子名称: | (2E,2'E)-3,3'-(1,2-phenylene)di(prop-2-enoic acid), DBB-DSG-VAL-MEA-VAL-GLY-GLY-DVA-DLE, kcn28 | 著者 | Shi, J, Liu, C.L, Zhang, B, Guo, W.J, Zhu, J.P, Xu, X, Xu, Q, Jiao, R.H, Tan, R.X, Ge, H.M. | 登録日 | 2019-01-03 | 公開日 | 2020-01-15 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.244 Å) | 主引用文献 | Genome mining and biosynthesis of kitacinnamycins as a STING activator. Chem Sci, 10, 2019
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4RD6
| Structure of aIF2-gamma from Sulfolobus solfataricus bound to GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Translation initiation factor 2 subunit gamma | 著者 | Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E. | 登録日 | 2014-09-18 | 公開日 | 2015-07-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.944 Å) | 主引用文献 | Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2. Nucleic Acids Res., 43, 2015
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5JWZ
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6PEG
| MIF with a allosteric inhibitor | 分子名称: | 4-amino-5-hydroxy-6-[(E)-(3-{[3-(2-methylpropanoyl)pyrazolo[1,5-a]pyridin-2-yl]methyl}phenyl)diazenyl]naphthalene-1,3-disulfonic acid, ACETATE ION, GLYCEROL, ... | 著者 | Asojo, O.A. | 登録日 | 2019-06-20 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inhibition of Macrophage Migration Inhibitory Factor by a Chimera of Two Allosteric Binders. Acs Med.Chem.Lett., 11, 2020
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6MYE
| Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF) | 分子名称: | FORMIC ACID, Protein scribble homolog, Rho guanine nucleotide exchange factor 26, ... | 著者 | Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J. | 登録日 | 2018-11-01 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility. J.Cell Biol., 218, 2019
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6YAL
| Mammalian 48S late-stage initiation complex with beta-globin mRNA | 分子名称: | 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ... | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | 登録日 | 2020-03-12 | 公開日 | 2020-04-08 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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5MPS
| Structure of a spliceosome remodeled for exon ligation | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | 登録日 | 2016-12-18 | 公開日 | 2017-01-18 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
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5NFZ
| TUBULIN-MTC complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-methoxy-5-(2,3,4-trimethoxyphenyl)cyclohepta-2,4,6-trien-1-one, CALCIUM ION, ... | 著者 | Field, J.J, Pera, B, Estevez Gallego, J, Calvo, E, Rodriguez-Salarichs, J, Saez-Calvo, G, Zuwerra, D, Jordi, M, Prota, A.E, Menchon, G, Miller, J.H, Altmann, K.-H, Diaz, J.F. | 登録日 | 2017-03-16 | 公開日 | 2017-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites. J. Nat. Prod., 81, 2018
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6N60
| Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-23 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.68 Å) | 主引用文献 | Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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