8PKI

Cryo-EM structure of NR5A2-nucleosome complex SHL+5.5

Summary for 8PKI

• Entry DOI: 10.2210/pdb8pki/pdb
• EMDB information: 17740
• Descriptor: Histone H3.3, Histone H4, Histone H2A, ... (8 entities in total)
• Functional Keywords: nucleosome, nuclear receptor, nr5a2, dna binding protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 11
• Total formula weight: 215229.85

Authors

Kobayashi, W.,Sappler, A.,Bollschweiler, D.,Kummecke, M.,Basquin, J.,Arslantas, E.,Ruangroengkulrith, S.,Hornberger, R.,Duderstadt, K.,Tachibana, K. (deposition date: 2023-06-26, release date: 2024-02-28, Last modification date: 2024-03-06)

• Primary citation: Kobayashi, W.,Sappler, A.H.,Bollschweiler, D.,Kummecke, M.,Basquin, J.,Arslantas, E.N.,Ruangroengkulrith, S.,Hornberger, R.,Duderstadt, K.,Tachibana, K.; Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition.; Nat.Struct.Mol.Biol., 2024; PubMed: 38409506; DOI: 10.1038/s41594-024-01239-0

Experimental method

ELECTRON MICROSCOPY (2.58 Å)