6UXM
Crystal structure of BAK core domain BH3-groove-dimer in complex with E. coli lipid
Summary for 6UXM
Entry DOI | 10.2210/pdb6uxm/pdb |
Descriptor | Bcl-2 homologous antagonist/killer, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (2 entities in total) |
Functional Keywords | pore-forming protein, apoptosis |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 61468.33 |
Authors | Cowan, A.D.,Colman, P.M.,Czabotar, P.E. (deposition date: 2019-11-07, release date: 2020-09-02, Last modification date: 2023-10-11) |
Primary citation | Cowan, A.D.,Smith, N.A.,Sandow, J.J.,Kapp, E.A.,Rustam, Y.H.,Murphy, J.M.,Brouwer, J.M.,Bernardini, J.P.,Roy, M.J.,Wardak, A.Z.,Tan, I.K.,Webb, A.I.,Gulbis, J.M.,Smith, B.J.,Reid, G.E.,Dewson, G.,Colman, P.M.,Czabotar, P.E. BAK core dimers bind lipids and can be bridged by them. Nat.Struct.Mol.Biol., 27:1024-1031, 2020 Cited by PubMed: 32929280DOI: 10.1038/s41594-020-0494-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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