6PEG

MIF with a allosteric inhibitor

Summary for 6PEG

Entry DOI	10.2210/pdb6peg/pdb
Descriptor	Macrophage migration inhibitory factor, ACETATE ION, GLYCEROL, ... (7 entities in total)
Functional Keywords	inhibitor, mif, drug discovery, isomerase
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	38587.32
Authors	Asojo, O.A. (deposition date: 2019-06-20, release date: 2019-11-27, Last modification date: 2023-10-11)
Primary citation	Cirillo, P.F.,Asojo, O.A.,Khire, U.,Lee, Y.,Mootien, S.,Hegan, P.,Sutherland, A.G.,Peterson-Roth, E.,Ledizet, M.,Koski, R.A.,Anthony, K.G. Inhibition of Macrophage Migration Inhibitory Factor by a Chimera of Two Allosteric Binders. Acs Med.Chem.Lett., 11:1843-1847, 2020 Cited by PubMed: 33062162 DOI: 10.1021/acsmedchemlett.9b00351 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation