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6PEG

MIF with a allosteric inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(D, E, F)
Macrophage migration inhibitory factorpolymer11412355.13UniProt (P14174)
Pfam (PF01187)
Homo sapiens (Human)MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase
2D, F, M, N
(D, F)
ACETATE IONnon-polymer59.04Chemie (ACT)
3E, L
(D, F)
GLYCEROLnon-polymer92.12Chemie (GOL)
4G, I, O
(D, E, F)
SULFATE IONnon-polymer96.13Chemie (SO4)
5H
(E)
4-amino-5-hydroxy-6-[(E)-(3-{[3-(2-methylpropanoyl)pyrazolo[1,5-a]pyridin-2-yl]methyl}phenyl)diazenyl]naphthalene-1,3-disulfonic acidnon-polymer623.71Chemie (4FQ)
6J, K
(E)
PHOSPHATE IONnon-polymer95.02Chemie (PO4)
7P, Q, R
(D, E, F)
waterwater18.0454Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight37065.2
Non-Polymers*Number of molecules12
Total formula weight1522.2
All*Total formula weight38587.3
*Water molecules are not included.

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PDB entries from 2025-06-25

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