7TIT

Cardiac thin filament decorated with regulatory M-domain of cardiac myosin binding protein C

Summary for 7TIT

• Entry DOI: 10.2210/pdb7tit/pdb
• EMDB information: 25914
• Descriptor: cardiac actin, Myosin-binding protein C, cardiac-type, tropomyosin model (3 entities in total)
• Functional Keywords: cardiac contraction regulator, muscle protein, motor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 16
• Total formula weight: 445830.75

Authors

Risi, C.M.,Galkin, V.E. (deposition date: 2022-01-14, release date: 2022-11-23, Last modification date: 2023-03-22)

• Primary citation: Risi, C.M.,Villanueva, E.,Belknap, B.,Sadler, R.L.,Harris, S.P.,White, H.D.,Galkin, V.E.; Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament.; J.Mol.Biol., 434:167879-167879, 2022; PubMed: 36370805; DOI: 10.1016/j.jmb.2022.167879

Experimental method

ELECTRON MICROSCOPY (8 Å)