8BY6
Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and cap-analogue m7GpppG
Summary for 8BY6
Entry DOI | 10.2210/pdb8by6/pdb |
EMDB information | 16321 |
Descriptor | Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, Nuclear cap-binding protein subunit 3, ... (4 entities in total) |
Functional Keywords | nuclear cap-binding complex, ncbp3, pol ii transcript metabolism, rna binding protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 115504.01 |
Authors | Dubiez, E.,Pellegrini, E.,Foucher, A.E.,Cusack, S.,Kadlec, J. (deposition date: 2022-12-12, release date: 2024-01-24, Last modification date: 2024-01-31) |
Primary citation | Dubiez, E.,Pellegrini, E.,Finderup Brask, M.,Garland, W.,Foucher, A.E.,Huard, K.,Heick Jensen, T.,Cusack, S.,Kadlec, J. Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43:113639-113639, 2024 Cited by PubMed: 38175753DOI: 10.1016/j.celrep.2023.113639 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.19 Å) |
Structure validation
Download full validation report