8BY6
Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and cap-analogue m7GpppG
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Nuclear cap-binding protein subunit 1 | polymer | 772 | 89810.0 | 1 | UniProt (Q09161) Pfam (PF02854) Pfam (PF09088) Pfam (PF09090) In PDB | Homo sapiens (human) | 80 kDa nuclear cap-binding protein,CBP80,NCBP 80 kDa subunit |
2 | B | Nuclear cap-binding protein subunit 2 | polymer | 158 | 18156.3 | 1 | UniProt (P52298) Pfam (PF00076) In PDB | Homo sapiens (human) | 20 kDa nuclear cap-binding protein,Cell proliferation-inducing gene 55 protein,NCBP 20 kDa subunit,CBP20,NCBP-interacting protein 1,NIP1 |
3 | C | Nuclear cap-binding protein subunit 3 | polymer | 60 | 6734.3 | 1 | UniProt (Q53F19) In PDB | Homo sapiens (human) | Protein ELG |
4 | B | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE | non-polymer | 803.4 | 1 | Chemie (GTG) |
Sequence modifications
A: 20 - 790 (UniProt: Q09161)
B: 1 - 156 (UniProt: P52298)
PDB | External Database | Details |
---|---|---|
Met 19 | - | initiating methionine |
Val 479 | Ala 479 | conflict |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 114700.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 803.4 | |
All* | Total formula weight | 115504.0 |