8BY6
Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and cap-analogue m7GpppG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear cap-binding protein subunit 1 | polymer | 772 | 89810.0 | 1 | UniProt (Q09161) Pfam (PF02854) Pfam (PF09088) Pfam (PF09090) | Homo sapiens (human) | 80 kDa nuclear cap-binding protein,CBP80,NCBP 80 kDa subunit |
| 2 | B (B) | Nuclear cap-binding protein subunit 2 | polymer | 158 | 18156.3 | 1 | UniProt (P52298) Pfam (PF00076) | Homo sapiens (human) | 20 kDa nuclear cap-binding protein,Cell proliferation-inducing gene 55 protein,NCBP 20 kDa subunit,CBP20,NCBP-interacting protein 1,NIP1 |
| 3 | C (C) | Nuclear cap-binding protein subunit 3 | polymer | 60 | 6734.3 | 1 | UniProt (Q53F19) | Homo sapiens (human) | Protein ELG |
| 4 | D (B) | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE | non-polymer | 803.4 | 1 | Chemie (GTG) |
Sequence modifications
A: 20 - 790 (UniProt: Q09161)
B: 1 - 156 (UniProt: P52298)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | initiating methionine |
| Val 479 | Ala 479 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 114700.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 803.4 | |
| All* | Total formula weight | 115504.0 |
