5NFZ

TUBULIN-MTC complex

Summary for 5NFZ

• Entry DOI: 10.2210/pdb5nfz/pdb
• Descriptor: Tubulin alpha-1B chain, GUANOSINE-5'-DIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (13 entities in total)
• Functional Keywords: cell cycle, tubulin fold, cytoskeleton, microtubule
• Biological source: Rattus norvegicus (Norway Rat); More
• Cellular location: Cytoplasm, cytoskeleton: P81947 Q6B856; Golgi apparatus : P63043
• Total number of polymer chains: 6
• Total formula weight: 265243.10

Authors

Field, J.J.,Pera, B.,Estevez Gallego, J.,Calvo, E.,Rodriguez-Salarichs, J.,Saez-Calvo, G.,Zuwerra, D.,Jordi, M.,Prota, A.E.,Menchon, G.,Miller, J.H.,Altmann, K.-H.,Diaz, J.F. (deposition date: 2017-03-16, release date: 2017-10-25, Last modification date: 2024-01-17)

• Primary citation: Field, J.J.,Pera, B.,Gallego, J.E.,Calvo, E.,Rodriguez-Salarichs, J.,Saez-Calvo, G.,Zuwerra, D.,Jordi, M.,Andreu, J.M.,Prota, A.E.,Menchon, G.,Miller, J.H.,Altmann, K.H.,Diaz, J.F.; Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites.; J. Nat. Prod., 81:494-505, 2018; PubMed: 29023132; DOI: 10.1021/acs.jnatprod.7b00704

Experimental method

X-RAY DIFFRACTION (2.1 Å)