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3K24
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Crystal structure of mature apo-Cathepsin L C25A mutant in complex with Gln-Leu-Ala peptide
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-6)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin L1, ...
著者Adams-Cioaba, M.A, Krupa, J.C, Mort, J.S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2009-09-29
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for the recognition and cleavage of histone H3 by cathepsin L.
Nat Commun, 2, 2011
2V83
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Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide
分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
4I0K
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BU of 4i0k by Molmil
Crystal structure of murine B7-H3 extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD276 antigen, SULFATE ION, ...
著者Vigdorovich, V, Ramagopal, U, Bonanno, J.B, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
登録日2012-11-16
公開日2012-12-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structure and T cell inhibition properties of B7 family member, B7-H3.
Structure, 21, 2013
3AVR
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BU of 3avr by Molmil
Catalytic fragment of UTX/KDM6A bound with histone H3K27me3 peptide, N-oxyalylglycine, and Ni(II)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Histone H3, ...
著者Sengoku, T, Yokoyama, S.
登録日2011-03-07
公開日2011-10-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A
Genes Dev., 25, 2011
2H68
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BU of 2h68 by Molmil
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-30
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2RVN
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BU of 2rvn by Molmil
Solution structure of the chromodomain of HP1a with the phosphorylated N-terminal tail complexed with H3K9me3 peptide
分子名称: 18-mer peptide of Histone H3, Chromobox protein homolog 5
著者Kawaguchi, A, Nishimura, Y.
登録日2015-12-18
公開日2016-03-16
実験手法SOLUTION NMR
主引用文献Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
6JM9
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cryo-EM structure of DOT1L bound to unmodified nucleosome
分子名称: DNA strand I, DNA strand J, Histone H2A, ...
著者Jang, S, Song, J.J.
登録日2019-03-07
公開日2019-05-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
Genes Dev., 33, 2019
6JMA
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cryo-EM structure of DOT1L bound to H2B ubiquitinated nucleosome
分子名称: DNA I&J, Histone H2A, Histone H2B 1.1, ...
著者Jang, S, Song, J.J.
登録日2019-03-07
公開日2019-05-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
Genes Dev., 33, 2019
2L75
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BU of 2l75 by Molmil
Solution structure of CHD4-PHD2 in complex with H3K9me3
分子名称: 14-meric peptide from 1Histone H3.1, Chromodomain-helicase-DNA-binding protein 4, ZINC ION
著者Mansfield, R.E, Kwan, A.H, Mackay, J.P.
登録日2010-12-02
公開日2011-01-19
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9
J.Biol.Chem., 286, 2011
2LGK
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BU of 2lgk by Molmil
NMR Structure of UHRF1 PHD domains in a complex with histone H3 peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION, histone H3 peptide
著者Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C.
登録日2011-07-28
公開日2011-09-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
2V89
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BU of 2v89 by Molmil
Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide at 1.1A resolution
分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-03
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Rag2 Phd Finger Couples Histone H3 Lysine 4 Trimethylation with V(D)J Recombination.
Nature, 450, 2007
3G7L
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BU of 3g7l by Molmil
Chromodomain of Chp1 in complex with Histone H3K9me3 peptide
分子名称: ACETIC ACID, Chromo domain-containing protein 1, Histone H3.1/H3.2, ...
著者Schalch, T, Joshua-Tor, L.
登録日2009-02-10
公開日2009-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin
Mol.Cell, 34, 2009
5CMA
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BU of 5cma by Molmil
Anti-B7-H3 monoclonal antibody ch8H9 Fab fragment
分子名称: Antibody ch8H9 Fab heavy chain, Antibody ch8H9 Fab light chain
著者Ahmed, M, Goldgur, Y, Cheng, M, Cheung, N.K.
登録日2015-07-16
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3.
J.Biol.Chem., 290, 2015
2LGG
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BU of 2lgg by Molmil
Structure of PHD domain of UHRF1 in complex with H3 peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION, histone H3 peptide
著者Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C.
登録日2011-07-26
公開日2011-09-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
4GY5
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BU of 4gy5 by Molmil
Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3
分子名称: E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION
著者Cheng, J, Yang, Y, Fang, J, Xiao, J, Zhu, T, Chen, F, Wang, P, Xu, Y.
登録日2012-09-05
公開日2012-11-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.956 Å)
主引用文献Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
J.Biol.Chem., 288, 2013
3RJ2
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BU of 3rj2 by Molmil
Structural and functional characterization of a novel histone H3 binding protein ORF158L from the Singapore grouper iridovirus (SGIV)
分子名称: Putative uncharacterized protein
著者Chen, L, Liu, Y, Sivaraman, J, Hew, C.L.
登録日2011-04-15
公開日2012-02-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Novel histone H3 binding protein ORF158L from the Singapore grouper iridovirus
J.Virol., 85, 2011
5VNB
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YEATS in complex with histone H3
分子名称: 1,2-ETHANEDIOL, H3K23acK27ac peptide, SULFATE ION, ...
著者Cho, H.J, Cierpicki, T.
登録日2017-04-29
公開日2018-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018
4H75
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BU of 4h75 by Molmil
Crystal structure of human Spindlin1 in complex with a histone H3K4(me3) peptide
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Histone H3, ...
著者Yang, N, Wang, W, Wang, Y, Wang, M, Zhao, Q, Rao, Z, Zhu, B, Xu, R.M.
登録日2012-09-20
公開日2012-10-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.098 Å)
主引用文献Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1.
Proc.Natl.Acad.Sci.USA, 109, 2012
4IGO
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BU of 4igo by Molmil
Histone H3 Lysine 4 Demethylating rice Rice JMJ703 in complex with alpha-KG
分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, Os05g0196500 protein
著者Chen, Q.F, Chen, X.S, Wang, Q, Zhang, F.B, Lou, Z.Y, Zhang, Q.F, Zhou, D.X.
登録日2012-12-17
公開日2013-04-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
PLoS Genet., 9, 2013
4IGP
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Histone H3 Lysine 4 Demethylating Rice JMJ703 apo enzyme
分子名称: FE (III) ION, Os05g0196500 protein
著者Chen, Q.F, Chen, X.S, Wang, Q, Zhang, F.B, Lou, Z.Y, Zhang, Q.F, Zhou, D.X.
登録日2012-12-17
公開日2013-04-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
PLoS Genet., 9, 2013
4IGQ
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Histone H3 Lysine 4 Demethylating Rice JMJ703 in complex with methylated H3K4 substrate
分子名称: FE (III) ION, N-OXALYLGLYCINE, Os05g0196500 protein, ...
著者Chen, Q.F, Chen, X.S, Wang, Q, Zhang, F.B, Lou, Z.Y, Zhang, Q.F, Zhou, D.X.
登録日2012-12-17
公開日2013-04-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
PLoS Genet., 9, 2013
2KVM
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BU of 2kvm by Molmil
Solution structure of the CBX7 chromodomain in complex with a H3K27me2 peptide
分子名称: Chromobox protein homolog 7, histone H3 peptide (residues 15-30) with dimethylated lysine 27
著者Yap, K.L, Zeng, L, Zhou, M.
登録日2010-03-17
公開日2010-06-30
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a.
Mol.Cell, 38, 2010
2VPB
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Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
分子名称: B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SODIUM ION, ...
著者Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
登録日2008-02-27
公開日2008-06-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2VP7
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Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
分子名称: B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SULFATE ION, ...
著者Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
登録日2008-02-26
公開日2008-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2VPD
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Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
分子名称: B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, ZINC ION
著者Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
登録日2008-02-27
公開日2008-06-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008

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