3AVR

Catalytic fragment of UTX/KDM6A bound with histone H3K27me3 peptide, N-oxyalylglycine, and Ni(II)

Summary for 3AVR

Related3AVS
DescriptorLysine-specific demethylase 6A, Histone H3, N-OXALYLGLYCINE, ... (8 entities in total)
Functional Keywordscupin superfamily, tri/dimethyllysine demethylase, oxidoreductase-structural protein complex, oxidoreductase/structural protein
Biological sourceHomo sapiens (human)
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Cellular locationNucleus (Probable) O15550
Total number of polymer chains2
Total molecular weight63478.89
Authors
Sengoku, T.,Yokoyama, S. (deposition date: 2011-03-07, release date: 2011-10-19, Last modification date: 2011-12-14)
Primary citation
Sengoku, T.,Yokoyama, S.
Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A
Genes Dev., 25:2266-2277, 2011
PubMed: 22002947 (PDB entries with the same primary citation)
DOI: 10.1101/gad.172296.111
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.803 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19360 1.6% 3.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02