4H75
Crystal structure of human Spindlin1 in complex with a histone H3K4(me3) peptide
Summary for 4H75
Entry DOI | 10.2210/pdb4h75/pdb |
Descriptor | Spindlin-1, Histone H3, GLYCEROL, ... (6 entities in total) |
Functional Keywords | tudor domain, h3k4me3 binding, methylation, gene regulation |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9Y657 |
Total number of polymer chains | 2 |
Total formula weight | 28692.46 |
Authors | |
Primary citation | Yang, N.,Wang, W.,Wang, Y.,Wang, M.,Zhao, Q.,Rao, Z.,Zhu, B.,Xu, R.M. Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1. Proc.Natl.Acad.Sci.USA, 109:17954-17959, 2012 Cited by PubMed: 23077255DOI: 10.1073/pnas.1208517109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.098 Å) |
Structure validation
Download full validation report