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4H75

Crystal structure of human Spindlin1 in complex with a histone H3K4(me3) peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Spindlin-1polymer23827128.71UniProt (Q9Y657)
Pfam (PF02513)
Homo sapiens (human)Ovarian cancer-related protein
2B
(B)
Histone H3polymer8976.21UniProt (Q5TEC6)Homo sapiens
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D, E, G
(A, B)
SULFATE IONnon-polymer96.13Chemie (SO4)
5F
(A)
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACIDnon-polymer207.31Chemie (NHE)
6H, I
(A, B)
waterwater18.0110Chemie (HOH)
Sequence modifications
A: 27 - 262 (UniProt: Q9Y657)
PDBExternal DatabaseDetails
Gly 25-expression tag
Ser 26-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28104.9
Non-Polymers*Number of molecules5
Total formula weight587.6
All*Total formula weight28692.5
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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