8REB
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8QOH
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![BU of 8qoh by Molmil](/molmil-images/mine/8qoh) | Crystal structure of the kinetoplastid kinetochore protein KKT14 C-terminal domain from Apiculatamorpha spiralis | 分子名称: | kinetochore protein KKT14 | 著者 | Carter, W, Ballmer, D, Ishii, M, Ludzia, P, Akiyoshi, B. | 登録日 | 2023-09-28 | 公開日 | 2024-01-17 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Kinetoplastid kinetochore proteins KKT14-KKT15 are divergent Bub1/BubR1-Bub3 proteins. Open Biology, 14, 2024
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8REA
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8R55
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![BU of 8r55 by Molmil](/molmil-images/mine/8r55) | Bacillus subtilis MutS2-collided disome complex (collided 70S) | 分子名称: | 16S rRNA (1533-MER), 23S RNA (2887-MER), 30S ribosomal protein S10, ... | 著者 | Park, E, Mackens-Kiani, T, Berhane, R, Esser, H, Erdenebat, C, Burroughs, A.M, Berninghausen, O, Aravind, L, Beckmann, R, Green, R, Buskirk, A.R. | 登録日 | 2023-11-16 | 公開日 | 2024-01-17 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage. Embo J., 43, 2024
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8RJD
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8RBR
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8RJB
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8RBX
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![BU of 8rbx by Molmil](/molmil-images/mine/8rbx) | Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | 登録日 | 2023-12-05 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
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8QLP
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![BU of 8qlp by Molmil](/molmil-images/mine/8qlp) | CryoEM structure of the RNA/DNA bound SPARTA (BabAgo/TIR-APAZ) tetrameric complex | 分子名称: | DNA (5'-D(*AP*CP*TP*AP*AP*TP*AP*GP*AP*TP*TP*AP*GP*AP*GP*CP*CP*GP*TP*C)-3'), MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ... | 著者 | Finocchio, G, Koopal, B, Potocnik, A, Heijstek, C, Jinek, M, Swarts, D. | 登録日 | 2023-09-20 | 公開日 | 2024-01-31 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic Acids Res., 52, 2024
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8RC4
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![BU of 8rc4 by Molmil](/molmil-images/mine/8rc4) | Structure of Integrator-PP2A complex | 分子名称: | DSS1, Integrator complex subunit 1, Integrator complex subunit 10, ... | 著者 | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | 登録日 | 2023-12-06 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
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8QLO
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![BU of 8qlo by Molmil](/molmil-images/mine/8qlo) | CryoEM structure of the apo SPARTA (BabAgo/TIR-APAZ) complex | 分子名称: | Short prokaryotic Argonaute, Toll/interleukin-1 receptor domain-containing protein | 著者 | Finocchio, G, Koopal, B, Potocnik, A, Heijstek, C, Jinek, M, Swarts, D. | 登録日 | 2023-09-20 | 公開日 | 2024-01-31 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic Acids Res., 52, 2024
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8QFZ
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![BU of 8qfz by Molmil](/molmil-images/mine/8qfz) | TSLP-Bicycle complex | 分子名称: | 1-[3,5-bis(3-bromanylpropanoyl)-1,3,5-triazinan-1-yl]-3-bromanyl-propan-1-one, CYS-HIS-TRP-LEU-GLU-ASN-CYS-TRP-ARG-GLY-PHE-CYS, Thymic stromal lymphopoietin | 著者 | Petersen, J. | 登録日 | 2023-09-05 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery and Characterization of a Bicyclic Peptide (Bicycle) Binder to Thymic Stromal Lymphopoietin. J.Med.Chem., 67, 2024
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4YCG
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![BU of 4ycg by Molmil](/molmil-images/mine/4ycg) | Pro-bone morphogenetic protein 9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone Morphogenetic Protein 9 Growth Factor Domain, Bone Morphogenetic Protein 9 Prodomain, ... | 著者 | Mi, L.-Z, Brown, C.T, Gao, Y, Tian, Y, Le, V, Walz, T, Springer, T.A. | 登録日 | 2015-02-20 | 公開日 | 2015-03-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of bone morphogenetic protein 9 procomplex. Proc.Natl.Acad.Sci.USA, 112, 2015
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4YDI
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![BU of 4ydi by Molmil](/molmil-images/mine/4ydi) | Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | 登録日 | 2015-02-22 | 公開日 | 2015-06-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.452 Å) | 主引用文献 | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell, 161, 2015
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8RBZ
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![BU of 8rbz by Molmil](/molmil-images/mine/8rbz) | Structure of Integrator-PP2A-SOSS-CTD post-termination complex | 分子名称: | DNA-directed RNA polymerase subunit, DSS1, Integrator complex subunit 1, ... | 著者 | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | 登録日 | 2023-12-05 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
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8RDX
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![BU of 8rdx by Molmil](/molmil-images/mine/8rdx) | PGGtase I in complex with probe BAY-6092 | 分子名称: | (5~{R})-5-(2-methoxyphenyl)-9-[(2~{R})-3,3,3-tris(fluoranyl)-2-methoxy-2-phenyl-propanoyl]-3,9-diazaspiro[5.5]undecan-2-one, CHLORIDE ION, DIPHOSPHATE, ... | 著者 | Steuber, H. | 登録日 | 2023-12-08 | 公開日 | 2024-02-14 | 最終更新日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (3.67 Å) | 主引用文献 | Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling. Cell Chem Biol, 31, 2024
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1ADV
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![BU of 1adv by Molmil](/molmil-images/mine/1adv) | EARLY E2A DNA-BINDING PROTEIN | 分子名称: | ADENOVIRUS SINGLE-STRANDED DNA-BINDING PROTEIN, ZINC ION | 著者 | Kanellopoulos, P.N, Tsernoglou, D, Van Der Vliet, P.C, Tucker, P.A. | 登録日 | 1995-05-12 | 公開日 | 1996-06-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Alternative arrangements of the protein chain are possible for the adenovirus single-stranded DNA binding protein. J.Mol.Biol., 257, 1996
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8QRT
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1AHN
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![BU of 1ahn by Molmil](/molmil-images/mine/1ahn) | E. COLI FLAVODOXIN AT 2.6 ANGSTROMS RESOLUTION | 分子名称: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Hoover, D.M, Ludwig, M.L. | 登録日 | 1997-04-07 | 公開日 | 1997-12-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A flavodoxin that is required for enzyme activation: the structure of oxidized flavodoxin from Escherichia coli at 1.8 A resolution. Protein Sci., 6, 1997
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8QS0
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8R1T
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![BU of 8r1t by Molmil](/molmil-images/mine/8r1t) | Pim1 in complex with 4-(4-aminophenethyl)benzoic acid and Pimtide | 分子名称: | 4-(4-aminophenethyl)benzoic acid, GLYCEROL, Pimtide, ... | 著者 | Hochban, P.M.M, Heine, A, Diederich, W.E. | 登録日 | 2023-11-02 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | What doesn't fit is made to fit: Pim-1 kinase adapts to the configuration of stilbene-based inhibitors. Arch Pharm, 357, 2024
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1AH8
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8QBT
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![BU of 8qbt by Molmil](/molmil-images/mine/8qbt) | E. coli ApdP-stalled ribosomal complex | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ... | 著者 | Morici, M, Wilson, D.N. | 登録日 | 2023-08-25 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity. Nat Commun, 15, 2024
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7ZVA
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![BU of 7zva by Molmil](/molmil-images/mine/7zva) | Crystal Structure of the native zymogen form of the glutamic-class prolyl-endopeptidase neprosin at 1.80 A resolution. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, C-terminal peptidase, ... | 著者 | Del Amo-Maestro, L, Eckhard, U, Rodriguez-Banqueri, A, Mendes, S.R, Guevara, T, Gomis-Ruth, F.X. | 登録日 | 2022-05-14 | 公開日 | 2022-08-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular and in vivo studies of a glutamate-class prolyl-endopeptidase for coeliac disease therapy. Nat Commun, 13, 2022
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7ZU8
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![BU of 7zu8 by Molmil](/molmil-images/mine/7zu8) | Crystal Structure of the zymogen form of the glutamic-class prolyl-endopeptidase neprosin at 2.05 A resolution in presence of the crystallophore Lu-Xo4. | 分子名称: | 12-oxidanyl-9,11$l^{3}-dioxa-1$l^{4},19$l^{4},22,27$l^{4},28$l^{4}-pentaza-10$l^{6}-lutetaoctacyclo[17.5.2.1^{3,7}.1^{10,13}.0^{1,10}.0^{10,19}.0^{10,28}.0^{17,27}]octacosa-3,5,7(28),11,13,15,17(27)-heptaen-8-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Del Amo-Maestro, L, Eckhard, U, Rodriguez-Banqueri, A, Mendes, S.R, Guevara, T, Gomis-Ruth, F.X. | 登録日 | 2022-05-11 | 公開日 | 2022-08-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Molecular and in vivo studies of a glutamate-class prolyl-endopeptidase for coeliac disease therapy. Nat Commun, 13, 2022
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