8RC4

Structure of Integrator-PP2A complex

Summary for 8RC4

• Entry DOI: 10.2210/pdb8rc4/pdb
• EMDB information: 19047
• Descriptor: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Integrator complex subunit 8, Integrator complex subunit 9, ... (18 entities in total)
• Functional Keywords: integrator complex, post-termination complex, rna polymerase ii, pol ii, rnapii, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 16
• Total formula weight: 1435164.97

Authors

Fianu, I.,Ochmann, M.,Walshe, J.L.,Cramer, P. (deposition date: 2023-12-06, release date: 2024-02-07, Last modification date: 2024-04-10)

• Primary citation: Fianu, I.,Ochmann, M.,Walshe, J.L.,Dybkov, O.,Cruz, J.N.,Urlaub, H.,Cramer, P.; Structural basis of Integrator-dependent RNA polymerase II termination.; Nature, 2024; PubMed: 38570683; DOI: 10.1038/s41586-024-07269-4

Experimental method

ELECTRON MICROSCOPY (3.1 Å)