PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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5UMN	Crystal structure of C05 VPGSGW mutant bound to H3 influenza hemagglutinin, HA1 subunit 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05 VPGSGW mutant, heavy chain, ... 著者 Wu, N.C, Wilson, I.A. 登録日 2017-01-27 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity. Nat Commun, 8, 2017
3NFP	Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain 分子名称: Heavy chain of Fab fragment of daclizumab, Interleukin-2 receptor subunit alpha, Light chain of Fab fragment of daclizumab 著者 Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. 登録日 2010-06-10 公開日 2010-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
6Z7Z	Porcine insulin in complex with the analytical antibody OXI-005 Fab 分子名称: Insulin, MAGNESIUM ION, OXI-005 Fab Heavy chain, ... 著者 Johansson, E. 登録日 2020-06-02 公開日 2020-12-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties. Protein Sci., 30, 2021
6Z7W	Human insulin in complex with the analytical antibody HUI-018 Fab 分子名称: HUI-018 Fab Heavy Chain, Insulin, MAb 6H10 light chain 著者 Johansson, E. 登録日 2020-06-02 公開日 2020-12-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties. Protein Sci., 30, 2021
6XCM	Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2020-06-08 公開日 2020-07-01 最終更新日 2020-09-02 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies. Cell, 182, 2020
6XCN	Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2020-06-08 公開日 2020-07-01 最終更新日 2020-09-02 実験手法 ELECTRON MICROSCOPY (3.66 Å) 主引用文献 Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies. Cell, 182, 2020
5EWI	Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90 分子名称: VRC38.01 Heavy Chain, VRC38.01 Light Chain 著者 Gorman, J, Kwong, P.D. 登録日 2015-11-20 公開日 2016-11-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5996 Å) 主引用文献 Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop. Immunity, 46, 2017
3TCL	Crystal Structure of HIV-1 Neutralizing Antibody CH04 分子名称: CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE 著者 Louder, R.K, McLellan, J.S, Pancera, M, Yang, Y, Zhang, B, Bonsignori, M, Kwong, P.D. 登録日 2011-08-09 公開日 2011-11-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.906 Å) 主引用文献 Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480, 2011
3J30	Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab CHK152 分子名称: CHK152 heavy chain, CHK152 light chain 著者 Sun, S, Xiang, Y, Rossmann, M.G. 登録日 2013-01-28 公開日 2013-04-24 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (16 Å) 主引用文献 Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization. Elife, 2, 2013
5F89	Structure of the Unliganded Fab from HIV-1 Neutralising Antibody CAP248-2B that Binds to the gp120 C-terminus - gp41 Interface 分子名称: CAP248-2B Heavy Chain, CAP248-2B Light Chain 著者 Wibmer, C.K, Gorman, J, Kwong, P.D. 登録日 2015-12-09 公開日 2016-12-21 最終更新日 2017-03-29 実験手法 X-RAY DIFFRACTION (2.7842 Å) 主引用文献 Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape. PLoS Pathog., 13, 2017
5TGB	Structure of chimeric 02-CB Fab, a VRC01-like germline antibody 分子名称: 02-CB Fab Heavy Chain, 02-CB Fab Light Chain 著者 Pancera, M. 登録日 2016-09-27 公開日 2016-11-09 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (2.741 Å) 主引用文献 Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors. Cell Rep, 17, 2016
5TFS	Structure of chimeric 02-K Fab, a VRC01-like germline antibody 分子名称: 02-K Fab Heavy chain, 02-K Fab Light chain, SULFATE ION 著者 Pancera, M. 登録日 2016-09-26 公開日 2016-11-09 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (2.319 Å) 主引用文献 Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors. Cell Rep, 17, 2016
8JOW	Crystal structure of rabbit antibody with phosphorylated peptide bound 分子名称: ARG-PRO-HIS-PHE-PRO-GLN-PHE-SEP-TYR-SER-ALA-SER, Antibody (scFv), CHLORIDE ION 著者 Caaveiro, J.M.M, Kawade, R, Tsumoto, K. 登録日 2023-06-08 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Origin of high binding affinity and selectivity of phosphorylated epitope-specific rabbit antibodies To Be Published
6Z7X	Insulin analytical antibody OXI-005 Fab 分子名称: OXI-005 Fab Heavy chain, OXI-005 Fab Light chain 著者 Johansson, E. 登録日 2020-06-02 公開日 2020-12-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties. Protein Sci., 30, 2021
6Z7Y	Human insulin in complex with the analytical antibody OXI-005 Fab 分子名称: Insulin, OXI-005 Fab Heavy chain, OXI-005 Fab Light chain 著者 Johansson, E. 登録日 2020-06-02 公開日 2020-12-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties. Protein Sci., 30, 2021
5TF1	Structure of chimeric 02-CC Fab, a VRC01-like germline antibody 分子名称: 02-CC Fab Heavy chain, O2-CC Fab Light Chain 著者 Pancera, M. 登録日 2016-09-23 公開日 2016-11-16 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (1.858 Å) 主引用文献 Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors. Cell Rep, 17, 2016
5GMQ	Structure of MERS-CoV RBD in complex with a fully human antibody MCA1 分子名称: 1,2-ETHANEDIOL, MCA1 heavy chain, MCA1 light chain, ... 著者 Chen, C, Wang, J.M, Zou, T.T, Gao, X.P, Cui, S, Jin, Q. 登録日 2016-07-15 公開日 2017-05-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset. J. Infect. Dis., 215, 2017
5U4M	RTA-V1C7-G29R-no_salt 分子名称: CHLORIDE ION, Ricin, V1C7 VHH antibody 著者 Rudolph, M.J, Mantis, N. 登録日 2016-12-05 公開日 2017-12-13 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies. Proteins, 85, 2017
3NFS	Crystal structure the Fab fragment of therapeutic antibody daclizumab 分子名称: Heavy chain of Fab fragment of daclizumab, Light chain of Fab fragment of daclizumab 著者 Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. 登録日 2010-06-10 公開日 2010-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
6N7J	BDBV223 Fab bound to synthetic peptide of Bundibugyo virus Glycoprotein Stalk 分子名称: BDBV223 antibody heavy chain, BDBV223 antibody light chain, Envelope glycoprotein 著者 King, L.B, West, B.R, Saphire, E.O. 登録日 2018-11-27 公開日 2019-03-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.684 Å) 主引用文献 Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun, 10, 2019
6GLX	Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 4E8 分子名称: Fab 4E8 - Heavy chain, Fab 4E8 - Light chain, Galectin-10 著者 Verstraete, K, Verschueren, K, Savvides, S.N. 登録日 2018-05-23 公開日 2019-06-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.396 Å) 主引用文献 Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019
6XC4	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 heavy chain, CC12.3 light chain, ... 著者 Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. 登録日 2020-06-08 公開日 2020-07-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.341 Å) 主引用文献 Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
6XC2	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 heavy chain, CC12.1 light chain, ... 著者 Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. 登録日 2020-06-08 公開日 2020-07-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.112 Å) 主引用文献 Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
1OAQ	Free conformation Ab1 of the IgE SPE-7 分子名称: HEAVY CHAIN, LIGHT CHAIN 著者 James, L.C, Roversi, P, Tawfik, D. 登録日 2003-01-21 公開日 2004-01-15 最終更新日 2013-10-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Antibody Multispecificity Mediated by Conformational Diversity Science, 299, 2003
6GLW	Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 1D11 分子名称: ACETATE ION, Fab 1D11 - Heavy chain, Fab 1D11 - Light chain, ... 著者 Verstraete, K, Verschueren, K, Savvides, S.N. 登録日 2018-05-23 公開日 2019-06-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364, 2019

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