6XC2

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC12.1

Summary for 6XC2

DescriptorSpike protein S1, CC12.1 light chain, CC12.1 heavy chain, ... (4 entities in total)
Functional Keywordsantibody, sars-cov-2, coronavirus, spike, immune system, immune system-viral protein complex, immune system/viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains6
Total molecular weight146217.67
Authors
Yuan, M.,Liu, H.,Wu, N.C.,Zhu, X.,Wilson, I.A. (deposition date: 2020-06-08, release date: 2020-07-08, Last modification date: 2020-07-29)
Primary citation
Yuan, M.,Liu, H.,Wu, N.C.,Lee, C.D.,Zhu, X.,Zhao, F.,Huang, D.,Yu, W.,Hua, Y.,Tien, H.,Rogers, T.F.,Landais, E.,Sok, D.,Jardine, J.G.,Burton, D.R.,Wilson, I.A.
Structural basis of a public antibody response to SARS-CoV-2.
Biorxiv, 2020
PubMed: 32577642 (PDB entries with the same primary citation)
DOI: 10.1101/2020.06.08.141267
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.112 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26710 0.2% 1.9% 1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
167518
PDB entries from 2020-08-12