6GLX

Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 4E8

Summary for 6GLX

Entry DOI	10.2210/pdb6glx/pdb
Descriptor	Galectin-10, Fab 4E8 - Heavy chain, Fab 4E8 - Light chain (3 entities in total)
Functional Keywords	fab, galectin-10, autocrystallizing, crystal solubilisation, sugar binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	136023.01
Authors	Verstraete, K.,Verschueren, K.,Savvides, S.N. (deposition date: 2018-05-23, release date: 2019-06-05, Last modification date: 2024-01-17)
Primary citation	Persson, E.K.,Verstraete, K.,Heyndrickx, I.,Gevaert, E.,Aegerter, H.,Percier, J.M.,Deswarte, K.,Verschueren, K.H.G.,Dansercoer, A.,Gras, D.,Chanez, P.,Bachert, C.,Goncalves, A.,Van Gorp, H.,De Haard, H.,Blanchetot, C.,Saunders, M.,Hammad, H.,Savvides, S.N.,Lambrecht, B.N. Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science, 364:-, 2019 Cited by PubMed: 31123109 DOI: 10.1126/science.aaw4295 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.396 Å)

Structure validation