5TF1
Structure of chimeric 02-CC Fab, a VRC01-like germline antibody
Summary for 5TF1
Entry DOI | 10.2210/pdb5tf1/pdb |
Related | 5TFS 5TGB |
Descriptor | 02-CC Fab Heavy chain, O2-CC Fab Light Chain (3 entities in total) |
Functional Keywords | fab, germline, vrc01-like, cd4-bs, hiv-1, cdrh3, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 49383.97 |
Authors | Pancera, M. (deposition date: 2016-09-23, release date: 2016-11-16, Last modification date: 2019-12-11) |
Primary citation | Yacoob, C.,Pancera, M.,Vigdorovich, V.,Oliver, B.G.,Glenn, J.A.,Feng, J.,Sather, D.N.,McGuire, A.T.,Stamatatos, L. Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors. Cell Rep, 17:1560-1570, 2016 Cited by PubMed: 27806295DOI: 10.1016/j.celrep.2016.10.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.858 Å) |
Structure validation
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