6GSA
 
 | | Core Centromere Binding Factor 3 (CBF3) with monomeric Ndc10 | | 分子名称: | Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... | | 著者 | Zhang, W.J, Lukoynova, N, Vaughan, C.K. | | 登録日 | 2018-06-13 | | 公開日 | 2018-08-01 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
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2L7M
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2LKX
 | | NMR structure of the homeodomain of Pitx2 in complex with a TAATCC DNA binding site | | 分子名称: | DNA (5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3'), Pituitary homeobox 3 | | 著者 | Baird-Titus, J.M, Doerdelmann, T, Chaney, B.A, Clark-Baldwin, K, Dave, V, Ma, J. | | 登録日 | 2011-10-21 | | 公開日 | 2012-05-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome
Biochemistry, 44, 2005
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5IBK
 | | Skp1-F-box in complex with a ubiquitin variant | | 分子名称: | F-box/WD repeat-containing protein 7, Polyubiquitin-B, S-phase kinase-associated protein 1,S-phase kinase-associated protein 1 | | 著者 | Orlicky, S, Sicheri, F. | | 登録日 | 2016-02-22 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | | 主引用文献 | Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5K35
 | | Structure of the Legionella effector, AnkB, in complex with human Skp1 | | 分子名称: | Ankyrin-repeat protein B, S-phase kinase-associated protein 1 | | 著者 | Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2016-05-19 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System.
Structure, 25, 2017
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6H5H
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2AST
 | | Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide | | 分子名称: | BENZAMIDINE, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... | | 著者 | Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P. | | 登録日 | 2005-08-24 | | 公開日 | 2005-10-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
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6C16
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2E31
 | | Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase | | 分子名称: | F-box only protein 2, S-phase kinase-associated protein 1A | | 著者 | Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K. | | 登録日 | 2006-11-20 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
Proc.Natl.Acad.Sci.Usa, 104, 2007
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6BVA
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6BYH
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2ASS
 | | Crystal structure of the Skp1-Skp2-Cks1 complex | | 分子名称: | BENZAMIDINE, Cyclin-dependent kinases regulatory subunit 1, PHOSPHATE ION, ... | | 著者 | Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P. | | 登録日 | 2005-08-24 | | 公開日 | 2005-10-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
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2E32
 | | Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase | | 分子名称: | F-box only protein 2, S-phase kinase-associated protein 1A | | 著者 | Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K. | | 登録日 | 2006-11-20 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | | 主引用文献 | Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
Proc.Natl.Acad.Sci.Usa, 104, 2007
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3BUY
 | | MHC-I in complex with peptide | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Rossjohn, J, La Gruta, N.L, Purcell, A.W, Turner, S.J, Dunstone, M.A. | | 登録日 | 2008-01-03 | | 公開日 | 2008-03-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides
Proc.Natl.Acad.Sci.Usa, 105, 2008
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6AC7
 | | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter | | 分子名称: | 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*GP*AP*GP*GP*CP*GP*GP*GP*GP*CP*TP*TP*GP*GP*G)-3' | | 著者 | Sengar, A, Vandana, J.J, Chambers, V.S, Di Antonio, M, Winnerdy, F.R, Balasubramanian, S, Phan, A.T. | | 登録日 | 2018-07-25 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter.
Nucleic Acids Res., 47, 2019
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8BYL
 | | Cryo-EM structure of SKP1-SKP2-CKS1 from the SCFSKP2 E3 ligase complex | | 分子名称: | Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, S-phase kinase-associated protein 1, ... | | 著者 | Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E.M. | | 登録日 | 2022-12-13 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
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3L2O
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2KWQ
 | | Mcm10 C-terminal DNA binding domain | | 分子名称: | Protein MCM10 homolog, ZINC ION | | 著者 | Robertson, P.D, Chagot, B, Chazin, W.J, Eichman, B.F. | | 登録日 | 2010-04-15 | | 公開日 | 2010-05-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif.
J.Biol.Chem., 285, 2010
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5V4B
 | | Crystal structure of the Skp1-FBXW7-DISC1 complex | | 分子名称: | DISC1 peptide, F-box/WD repeat-containing protein 7, IMIDAZOLE, ... | | 著者 | Li, Y, Baillie, G.S, Hao, B. | | 登録日 | 2017-03-08 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system.
Mol. Psychiatry, 23, 2018
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5VZT
 | | Crystal structure of the Skp1-FBXO31 complex | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, F-box only protein 31, PHOSPHATE ION, ... | | 著者 | Li, Y, Jin, K, Hao, B. | | 登録日 | 2017-05-29 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1LDK
 | | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex | | 分子名称: | CULLIN HOMOLOG, CYCLIN A/CDK2-ASSOCIATED PROTEIN P19, SKP2-like protein type gamma, ... | | 著者 | Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P. | | 登録日 | 2002-04-08 | | 公開日 | 2002-05-08 | | 最終更新日 | 2019-11-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
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5VZU
 | | Crystal structure of the Skp1-FBXO31-cyclin D1 complex | | 分子名称: | Cyclin D1, F-box only protein 31, PHOSPHATE ION, ... | | 著者 | Li, Y, Jin, K, Hao, B. | | 登録日 | 2017-05-29 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2OVQ
 | | Structure of the Skp1-Fbw7-CyclinEdegC complex | | 分子名称: | F-box/WD repeat protein 7, S-phase kinase-associated protein 1A, SULFATE ION, ... | | 著者 | Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P. | | 登録日 | 2007-02-14 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
Mol.Cell, 26, 2007
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2OVP
 | | Structure of the Skp1-Fbw7 complex | | 分子名称: | F-box/WD repeat protein 7, S-phase kinase-associated protein 1A | | 著者 | Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P. | | 登録日 | 2007-02-14 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
Mol.Cell, 26, 2007
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2OVR
 | | Structure of the Skp1-Fbw7-CyclinEdegN complex | | 分子名称: | F-box/WD repeat protein 7, S-phase kinase-associated protein 1A, SULFATE ION, ... | | 著者 | Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P. | | 登録日 | 2007-02-14 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
Mol.Cell, 26, 2007
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