8BYL

Cryo-EM structure of SKP1-SKP2-CKS1 from the SCFSKP2 E3 ligase complex

Summary for 8BYL

• Entry DOI: 10.2210/pdb8byl/pdb
• Related: 8BYA
• EMDB information: 16325 16327
• Descriptor: S-phase kinase-associated protein 1, S-phase kinase-associated protein 2, Cyclin-dependent kinases regulatory subunit 1, ... (4 entities in total)
• Functional Keywords: cell cycle, cyclin-dependent kinase, signalling, ubiquitinationcell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 98365.26

Authors

Rowland, R.J.,Salamina, M.,Endicott, J.A.,Noble, M.E.M. (deposition date: 2022-12-13, release date: 2023-06-28, Last modification date: 2023-07-19)

• Primary citation: Rowland, R.J.,Heath, R.,Maskell, D.,Thompson, R.F.,Ranson, N.A.,Blaza, J.N.,Endicott, J.A.,Noble, M.E.M.,Salamina, M.; Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.; Sci Rep, 13:10718-10718, 2023; PubMed: 37400515; DOI: 10.1038/s41598-023-37609-9

Experimental method

ELECTRON MICROSCOPY (3.5 Å)