8B0Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b0y by Molmil](/molmil-images/mine/8b0y) | cryo-EM structure of carboxysomal mini-shell: icosahedral assembly from CsoS4A/1A co-expression (T = 3) | 分子名称: | Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A | 著者 | Ni, T, Jiang, Q, Liu, L.N, Zhang, P. | 登録日 | 2022-09-08 | 公開日 | 2023-08-23 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Intrinsically disordered CsoS2 acts as a general molecular thread for alpha-carboxysome shell assembly. Nat Commun, 14, 2023
|
|
5BXQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bxq by Molmil](/molmil-images/mine/5bxq) | Structure of the NTF2:RanGDP complex | 分子名称: | GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Stewart, M. | 登録日 | 2015-06-09 | 公開日 | 2015-07-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran. J.Mol.Biol., 277, 1998
|
|
8GUW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8guw by Molmil](/molmil-images/mine/8guw) | |
2V50
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2v50 by Molmil](/molmil-images/mine/2v50) | |
8B11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b11 by Molmil](/molmil-images/mine/8b11) | cryo-EM structure of carboxysomal mini-shell: icosahedral assembly from CsoS4A/1A and CsoS2 co-expression (T = 4) | 分子名称: | Carboxysome shell vertex protein CsoS4A, Major carboxysome shell protein CsoS1A | 著者 | Ni, T, Jiang, Q, Liu, L.N, Zhang, P. | 登録日 | 2022-09-08 | 公開日 | 2023-08-23 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | 主引用文献 | Intrinsically disordered CsoS2 acts as a general molecular thread for alpha-carboxysome shell assembly. Nat Commun, 14, 2023
|
|
7DZ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dz5 by Molmil](/molmil-images/mine/7dz5) | Crystal structures of D-allulose 3-epimerase with D-sorbose from Sinorhizobium fredii | 分子名称: | D-sorbose, D-tagatose 3-epimerase, MAGNESIUM ION, ... | 著者 | Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. | 登録日 | 2021-01-23 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening Angew.Chem.Int.Ed.Engl., 2023
|
|
7EL7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7el7 by Molmil](/molmil-images/mine/7el7) | NMR solution structure of the 1:1 complex of a quadruplex-duplex hybrid MYT1L and a platinum(II) ligand L1Pt(dien) | 分子名称: | G-quadruplex DNA MYT1L, Pt(diethylenetriamine)(2-(pyridin-4-ylmethyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone) | 著者 | Liu, L.-Y, Liu, W, Mao, Z.-W. | 登録日 | 2021-04-08 | 公開日 | 2021-12-15 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Spatial Matching Selectivity and Solution Structure of Organic-Metal Hybrid to Quadruplex-Duplex Hybrid. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
6PIV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6piv by Molmil](/molmil-images/mine/6piv) | Crystal structure of HCV NS3/4A D168A protease in complex with P4-7 (NR03-77) | 分子名称: | (1R,3r,5S)-bicyclo[3.1.0]hexan-3-yl [(2R,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl]carbamate, 1,2-ETHANEDIOL, NS3/4A protease, ... | 著者 | Zephyr, J, Schiffer, C.A. | 登録日 | 2019-06-27 | 公開日 | 2020-03-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors. Mbio, 11, 2020
|
|
6PJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pj0 by Molmil](/molmil-images/mine/6pj0) | Crystal structure of HCV NS3/4A D168A protease in complex with P4-5 (NR01-97) | 分子名称: | 1,2-ETHANEDIOL, 1-ethylcyclopentyl [(2R,6S,12Z,13aS,14aR,16aS)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14a-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl]carbamate, NS3/4 Aprotease, ... | 著者 | Zephyr, J, Schiffer, C.A. | 登録日 | 2019-06-27 | 公開日 | 2020-03-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors. Mbio, 11, 2020
|
|
8B1N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b1n by Molmil](/molmil-images/mine/8b1n) | Crystal structure of TrmD-Tm1570 from Calditerrivibrio nitroreducens in complex with S-adenosyl-L-methionine | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Kluza, A, Lewandowska, I, Augustyniak, R, Sulkowska, J. | 登録日 | 2022-09-10 | 公開日 | 2022-09-28 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Are there double knots in proteins? Prediction and in vitro verification based on TrmD-Tm1570 fusion from C. nitroreducens. Front Mol Biosci, 10, 2023
|
|
7EPB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7epb by Molmil](/molmil-images/mine/7epb) | Cryo-EM structure of LY354740-bound mGlu2 homodimer | 分子名称: | (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, Anti-RON nanobody, Metabotropic glutamate receptor 2 | 著者 | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
|
|
7EPC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7epc by Molmil](/molmil-images/mine/7epc) | Cryo-EM structure of inactive mGlu7 homodimer | 分子名称: | Isoform 3 of Metabotropic glutamate receptor 7 | 著者 | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
|
|
7EPA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7epa by Molmil](/molmil-images/mine/7epa) | Cryo-EM structure of inactive mGlu2 homodimer | 分子名称: | Metabotropic glutamate receptor 2 | 著者 | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
|
|
7EPD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7epd by Molmil](/molmil-images/mine/7epd) | Cryo-EM structure of inactive mGlu2-7 heterodimer | 分子名称: | Isoform 3 of Metabotropic glutamate receptor 7, Metabotropic glutamate receptor 2,Peptidylprolyl isomerase | 著者 | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
|
|
7EPF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7epf by Molmil](/molmil-images/mine/7epf) | Crystal structure of mGlu2 bound to NAM597 | 分子名称: | (8~{R})-4-[2,4-bis(fluoranyl)phenyl]-8-methyl-7-[(2-methylpyrazol-3-yl)methyl]-6,8-dihydro-5~{H}-1,7-naphthyridine-2-carboxamide, FLAVIN MONONUCLEOTIDE, Metabotropic glutamate receptor 2 | 著者 | Du, J, Wang, D, Lin, S, Han, S, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
|
|
7EPE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7epe by Molmil](/molmil-images/mine/7epe) | Crystal structure of mGlu2 bound to NAM563 | 分子名称: | 4-(1-methylpyrazol-4-yl)-7-[[(2~{S})-2-(trifluoromethyl)morpholin-4-yl]methyl]quinoline-2-carboxamide, FLAVIN MONONUCLEOTIDE, Metabotropic glutamate receptor 2 | 著者 | Du, J, Wang, D, Lin, S, Han, S, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
|
|
8GAR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gar by Molmil](/molmil-images/mine/8gar) | |
7F1R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f1r by Molmil](/molmil-images/mine/7f1r) | Cryo-EM structure of the chemokine receptor CCR5 in complex with RANTES and Gi | 分子名称: | C-C motif chemokine 5,C-C chemokine receptor type 5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B. | 登録日 | 2021-06-09 | 公開日 | 2021-07-14 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nat Commun, 12, 2021
|
|
8GKH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gkh by Molmil](/molmil-images/mine/8gkh) | Structure of the Spizellomyces punctatus Fanzor (SpuFz) in complex with omega RNA and target DNA | 分子名称: | DNA (35-MER), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), MAGNESIUM ION, ... | 著者 | Xu, P, Saito, M, Zhang, F. | 登録日 | 2023-03-19 | 公開日 | 2023-07-05 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Fanzor is a eukaryotic programmable RNA-guided endonuclease. Nature, 620, 2023
|
|
7F1T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f1t by Molmil](/molmil-images/mine/7f1t) | Crystal structure of the human chemokine receptor CCR5 in complex with MIP-1a | 分子名称: | C-C motif chemokine 3,C-C chemokine receptor type 5,Rubredoxin,C-C chemokine receptor type 5, ZINC ION | 著者 | Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B. | 登録日 | 2021-06-09 | 公開日 | 2021-07-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nat Commun, 12, 2021
|
|
7F1Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f1q by Molmil](/molmil-images/mine/7f1q) | Cryo-EM structure of the chemokine receptor CCR5 in complex with MIP-1a and Gi | 分子名称: | C-C motif chemokine 3,C-C chemokine receptor type 5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhang, H, Chen, K, Tan, Q, Han, S, Zhu, Y, Zhao, Q, Wu, B. | 登録日 | 2021-06-09 | 公開日 | 2021-07-14 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nat Commun, 12, 2021
|
|
7EV9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ev9 by Molmil](/molmil-images/mine/7ev9) | cryoEM structure of particulate methane monooxygenase associated with Cu(I) | 分子名称: | Ammonia monooxygenase/methane monooxygenase, subunit C family protein, COPPER (I) ION, ... | 著者 | Chang, W.H, Lin, H.H, Tsai, I.K, Huang, S.H, Chung, S.C, Tu, I.P, Yu, S.F, Chan, S.I. | 登録日 | 2021-05-20 | 公開日 | 2021-07-21 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Copper Centers in the Cryo-EM Structure of Particulate Methane Monooxygenase Reveal the Catalytic Machinery of Methane Oxidation. J.Am.Chem.Soc., 143, 2021
|
|
7F3O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f3o by Molmil](/molmil-images/mine/7f3o) | Crystal structure of the GluA2o LBD in complex with glutamate and TAK-653 | 分子名称: | 7-(4-cyclohexyloxyphenyl)-9-methyl-4$l^{6}-thia-1$l^{4},5,8-triazabicyclo[4.4.0]deca-1(10),6,8-triene 4,4-dioxide, ACETATE ION, GLUTAMIC ACID, ... | 著者 | Sogabe, S, Igaki, S, Hirokawa, A, Zama, Y, Lane, W, Snell, G. | 登録日 | 2021-06-16 | 公開日 | 2021-07-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Strictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvement. Sci Rep, 11, 2021
|
|
5C94
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c94 by Molmil](/molmil-images/mine/5c94) | Infectious bronchitis virus nsp9 | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Non-structural protein 9 | 著者 | Chen, C, Dou, Y, Yang, H, Su, D. | 登録日 | 2015-06-26 | 公開日 | 2016-06-29 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.438 Å) | 主引用文献 | Structural basis for dimerization and RNA binding of avian infectious bronchitis virus nsp9. Protein Sci., 26, 2017
|
|
7FCA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7fca by Molmil](/molmil-images/mine/7fca) | PfkB(Mycobacterium marinum) | 分子名称: | Fructokinase, PfkB, GLYCEROL, ... | 著者 | Li, J, Gao, B, Ji, R. | 登録日 | 2021-07-14 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structural analysis and functional study of phosphofructokinase B (PfkB) from Mycobacterium marinum. Biochem.Biophys.Res.Commun., 579, 2021
|
|