7F1R
Cryo-EM structure of the chemokine receptor CCR5 in complex with RANTES and Gi
Summary for 7F1R
Entry DOI | 10.2210/pdb7f1r/pdb |
EMDB information | 31423 |
Descriptor | C-C motif chemokine 5,C-C chemokine receptor type 5, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (4 entities in total) |
Functional Keywords | g protein-coupled receptor, chemokine receptor ccr5, rantes, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 137826.44 |
Authors | |
Primary citation | Zhang, H.,Chen, K.,Tan, Q.,Shao, Q.,Han, S.,Zhang, C.,Yi, C.,Chu, X.,Zhu, Y.,Xu, Y.,Zhao, Q.,Wu, B. Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nat Commun, 12:4151-4151, 2021 Cited by PubMed: 34230484DOI: 10.1038/s41467-021-24438-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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