8GKH

Structure of the Spizellomyces punctatus Fanzor (SpuFz) in complex with omega RNA and target DNA

Summary for 8GKH

• Entry DOI: 10.2210/pdb8gkh/pdb
• EMDB information: 40184
• Descriptor: DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), Maltodextrin-binding protein (Fragment),OrfB_Zn_ribbon domain-containing protein, DNA (35-MER), ... (7 entities in total)
• Functional Keywords: fanzor, eukaryotic, rna-guided, nuclease, gene editing, rna binding protein, rna binding protein-rna-dna complex, rna binding protein/rna/dna
• Biological source: Methanosarcina mazei; More
• Total number of polymer chains: 4
• Total formula weight: 158527.65

Authors

Xu, P.,Saito, M.,Zhang, F. (deposition date: 2023-03-19, release date: 2023-07-05, Last modification date: 2023-08-30)

• Primary citation: Saito, M.,Xu, P.,Faure, G.,Maguire, S.,Kannan, S.,Altae-Tran, H.,Vo, S.,Desimone, A.,Macrae, R.K.,Zhang, F.; Fanzor is a eukaryotic programmable RNA-guided endonuclease.; Nature, 620:660-668, 2023; PubMed: 37380027; DOI: 10.1038/s41586-023-06356-2

Experimental method

ELECTRON MICROSCOPY (2.7 Å)