8GUW

Structure of Aurora Kinase A in complex with activator peptide

Summary for 8GUW

Entry DOI	10.2210/pdb8guw/pdb
Descriptor	Peptide from Centrosomal protein of 192 kDa,Aurora kinase A, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	complex, kinase, cytosolic protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	106623.29
Authors	Lee, I.-G.,Park, J. (deposition date: 2022-09-13, release date: 2023-05-31, Last modification date: 2023-11-29)
Primary citation	Park, J.G.,Jeon, H.,Shin, S.,Song, C.,Lee, H.,Kim, N.K.,Kim, E.E.,Hwang, K.Y.,Lee, B.J.,Lee, I.G. Structural basis for CEP192-mediated regulation of centrosomal AURKA. Sci Adv, 9:eadf8582-eadf8582, 2023 Cited by PubMed: 37083534 DOI: 10.1126/sciadv.adf8582 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation