7EPE
Crystal structure of mGlu2 bound to NAM563
Summary for 7EPE
Entry DOI | 10.2210/pdb7epe/pdb |
Descriptor | Metabotropic glutamate receptor 2, FLAVIN MONONUCLEOTIDE, 4-(1-methylpyrazol-4-yl)-7-[[(2~{S})-2-(trifluoromethyl)morpholin-4-yl]methyl]quinoline-2-carboxamide (3 entities in total) |
Functional Keywords | membrane protein, gpcr |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 49372.32 |
Authors | |
Primary citation | Du, J.,Wang, D.,Fan, H.,Xu, C.,Tai, L.,Lin, S.,Han, S.,Tan, Q.,Wang, X.,Xu, T.,Zhang, H.,Chu, X.,Yi, C.,Liu, P.,Wang, X.,Zhou, Y.,Pin, J.P.,Rondard, P.,Liu, H.,Liu, J.,Sun, F.,Wu, B.,Zhao, Q. Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594:589-593, 2021 Cited by PubMed: 34135509DOI: 10.1038/s41586-021-03641-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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