7F1T

Crystal structure of the human chemokine receptor CCR5 in complex with MIP-1a

Summary for 7F1T

• Entry DOI: 10.2210/pdb7f1t/pdb
• Descriptor: C-C motif chemokine 3,C-C chemokine receptor type 5,Rubredoxin,C-C chemokine receptor type 5, ZINC ION (2 entities in total)
• Functional Keywords: g protein-coupled receptor, chemokine receptor ccr5, mip-1a, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 55510.86

Authors

Zhang, H.,Chen, K.,Tan, Q.,Han, S.,Zhu, Y.,Zhao, Q.,Wu, B. (deposition date: 2021-06-09, release date: 2021-07-14, Last modification date: 2023-11-29)

• Primary citation: Zhang, H.,Chen, K.,Tan, Q.,Shao, Q.,Han, S.,Zhang, C.,Yi, C.,Chu, X.,Zhu, Y.,Xu, Y.,Zhao, Q.,Wu, B.; Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5.; Nat Commun, 12:4151-4151, 2021; PubMed: 34230484; DOI: 10.1038/s41467-021-24438-5

Experimental method

X-RAY DIFFRACTION (2.6 Å)