4QG6
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![BU of 4qg6 by Molmil](/molmil-images/mine/4qg6) | crystal structure of PKM2-Y105E mutant | 分子名称: | PROLINE, Pyruvate kinase PKM | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | 登録日 | 2014-05-22 | 公開日 | 2015-02-25 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.207 Å) | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2. Protein Cell, 6, 2015
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4EIJ
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4UMO
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1MXG
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![BU of 1mxg by Molmil](/molmil-images/mine/1mxg) | Crystal Structure of a (Ca,Zn)-dependent alpha-amylase from the hyperthermophilic archaeon Pyrococcus woesei in complex with acarbose | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | 著者 | Linden, A, Mayans, O, Meyer-Klaucke, W, Antranikian, G, Wilmanns, M. | 登録日 | 2002-10-02 | 公開日 | 2003-06-10 | 最終更新日 | 2020-09-09 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Differential Regulation of a Hyperthermophilic alpha-Amylase with a Novel (Ca,Zn) Two-metal Center by Zinc J.Biol.Chem., 278, 2003
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1W6U
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![BU of 1w6u by Molmil](/molmil-images/mine/1w6u) | Structure of human DECR ternary complex | 分子名称: | 2,4-DIENOYL-COA REDUCTASE, MITOCHONDRIAL PRECURSOR, HEXANOYL-COENZYME A, ... | 著者 | Alphey, M.S, Byres, E, Li, D, Hunter, W.N. | 登録日 | 2004-08-24 | 公開日 | 2004-10-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure and Reactivity of Human Mitochondrial 2,4-Dienoyl-Coa Reductase: Enzyme-Ligand Interactions in a Distinctive Short-Chain Reductase Active Site J.Biol.Chem., 280, 2005
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6E2F
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8BZF
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![BU of 8bzf by Molmil](/molmil-images/mine/8bzf) | FC-J acetonide stabilizer of 14-3-3 and ERalpha | 分子名称: | 14-3-3 protein sigma, ERalpha peptide, Fusicoccin J-acetonide, ... | 著者 | Visser, E.J, Ottmann, C. | 登録日 | 2022-12-14 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Stabilization of the Estrogen receptor alpha - 14-3-3 interaction as a potential intervention strategy for endocrine resistance in breast cancer To Be Published
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1MSD
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![BU of 1msd by Molmil](/molmil-images/mine/1msd) | COMPARISON OF THE CRYSTAL STRUCTURES OF GENETICALLY ENGINEERED HUMAN MANGANESE SUPEROXIDE DISMUTASE AND MANGANESE SUPEROXIDE DISMUTASE FROM THERMUS THERMOPHILUS. DIFFERENCES IN DIMER-DIMER INTERACTIONS. | 分子名称: | MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE | 著者 | Sussman, J, Wagner, U.G, Pattridge, K.A, Ludwig, M.L. | 登録日 | 1992-11-10 | 公開日 | 1993-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Comparison of the crystal structures of genetically engineered human manganese superoxide dismutase and manganese superoxide dismutase from Thermus thermophilus: differences in dimer-dimer interaction. Protein Sci., 2, 1993
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7D7E
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![BU of 7d7e by Molmil](/molmil-images/mine/7d7e) | Structure of PKD1L3-CTD/PKD2L1 in apo state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Polycystic kidney disease 2-like 1 protein, ... | 著者 | Su, Q, Chen, M, Li, B, Wang, Y, Jing, D, Zhan, X, Yu, Y, Shi, Y. | 登録日 | 2020-10-03 | 公開日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for Ca 2+ activation of the heteromeric PKD1L3/PKD2L1 channel. Nat Commun, 12, 2021
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4GFK
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![BU of 4gfk by Molmil](/molmil-images/mine/4gfk) | structures of NO factors | 分子名称: | Nucleoid occlusion factor SlmA | 著者 | Schumacher, M.A. | 登録日 | 2012-08-03 | 公開日 | 2013-06-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid. Proc.Natl.Acad.Sci.USA, 110, 2013
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7T37
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![BU of 7t37 by Molmil](/molmil-images/mine/7t37) | Activated state of 2-APB and CBD-bound wildtype rat TRPV2 in nanodiscs | 分子名称: | 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2, cannabidiol | 著者 | Pumroy, R.A, Protopopova, A.D, Gallo, P.N, Moiseenkova-Bell, V.Y. | 登録日 | 2021-12-07 | 公開日 | 2022-05-04 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insights into TRPV2 activation by small molecules. Nat Commun, 13, 2022
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4QG8
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![BU of 4qg8 by Molmil](/molmil-images/mine/4qg8) | crystal structure of PKM2-K305Q mutant | 分子名称: | GLYCEROL, MAGNESIUM ION, MALONATE ION, ... | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | 登録日 | 2014-05-22 | 公開日 | 2015-02-25 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2. Protein Cell, 6, 2015
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7RX0
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![BU of 7rx0 by Molmil](/molmil-images/mine/7rx0) | Complex of AMPPNP-Kif7 and Gli2 Zinc-Finger domain bound to microtubules | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF7, MAGNESIUM ION, ... | 著者 | Mani, N, Wilson-Kubalek, E.M, Haque, F, Freniere, C, Milligan, R.A, Subramanian, R. | 登録日 | 2021-08-20 | 公開日 | 2022-06-15 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | 主引用文献 | Cytoskeletal regulation of a transcription factor by DNA mimicry via coiled-coil interactions. Nat.Cell Biol., 24, 2022
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7DNI
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![BU of 7dni by Molmil](/molmil-images/mine/7dni) | MDA5 CARDs-MAVS CARD polyUb complex | 分子名称: | Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin | 著者 | Song, B, Chen, Y, Luo, D.H, Zheng, J. | 登録日 | 2020-12-09 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains. Immunity, 54, 2021
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4UZL
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2J9R
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![BU of 2j9r by Molmil](/molmil-images/mine/2j9r) | Thymidine kinase from B. anthracis in complex with dT. | 分子名称: | PHOSPHATE ION, THYMIDINE, THYMIDINE KINASE, ... | 著者 | Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H. | 登録日 | 2006-11-15 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding FEBS J., 274, 2007
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4Y33
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![BU of 4y33 by Molmil](/molmil-images/mine/4y33) | Crystal of NO66 in complex with Ni(II)and N-oxalylglycine (NOG) | 分子名称: | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, N-OXALYLGLYCINE, NICKEL (II) ION | 著者 | Wang, C, Zhang, Q, Zang, J. | 登録日 | 2015-02-10 | 公開日 | 2015-10-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the JmjC domain-containing protein NO66 complexed with ribosomal protein Rpl8. Acta Crystallogr.,Sect.D, 71, 2015
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4QG9
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![BU of 4qg9 by Molmil](/molmil-images/mine/4qg9) | crystal structure of PKM2-R399E mutant | 分子名称: | ACETATE ION, MAGNESIUM ION, Pyruvate kinase PKM | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | 登録日 | 2014-05-22 | 公開日 | 2015-02-25 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.381 Å) | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2. Protein Cell, 6, 2015
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4Y49
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6YL2
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![BU of 6yl2 by Molmil](/molmil-images/mine/6yl2) | Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism | 分子名称: | DNA (5'-D(*AP*CP*GP*TP*TP*AP*AP*TP*GP*AP*CP*GP*AP*TP*TP*AP*AP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*TP*TP*AP*AP*TP*CP*GP*TP*CP*AP*TP*TP*AP*AP*CP*GP*T)-3'), Probable transcriptional regulatory protein (Probably TetR-family) | 著者 | Keep, N.H, Pritchard, J.E, Sula, A, Cole, A.R, Kendall, S.L. | 登録日 | 2020-04-06 | 公開日 | 2021-04-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism To be published
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4R9W
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![BU of 4r9w by Molmil](/molmil-images/mine/4r9w) | Crystal structure of platelet factor 4 complexed with fondaparinux | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, Platelet factor 4 | 著者 | Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. | 登録日 | 2014-09-08 | 公開日 | 2015-12-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6, 2015
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4R9Y
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![BU of 4r9y by Molmil](/molmil-images/mine/4r9y) | Crystal structure of KKOFab in complex with platelet factor 4 | 分子名称: | Platelet factor 4, Platelet factor 4 antibody KKO heavy chain, Platelet factor 4 antibody KKO light chain | 著者 | Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. | 登録日 | 2014-09-08 | 公開日 | 2015-12-16 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (4.11 Å) | 主引用文献 | Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6, 2015
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8E94
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![BU of 8e94 by Molmil](/molmil-images/mine/8e94) | PYD-106-bound Human GluN1a-GluN2C NMDA receptor in intact conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
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1GLI
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8E97
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![BU of 8e97 by Molmil](/molmil-images/mine/8e97) | PYD-106-bound Human GluN1a-GluN2C NMDA receptor in splayed conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
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