6E2F

Cryo-EM structure of human TRPV6 in complex with Calmodulin

Summary for 6E2F

• Entry DOI: 10.2210/pdb6e2f/pdb
• EMDB information: 8961
• Descriptor: Transient receptor potential cation channel subfamily V member 6, Calmodulin-1, CALCIUM ION (3 entities in total)
• Functional Keywords: trpv6, trp channels, calcium channels, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 350304.32

Authors

Singh, A.K.,McGoldrick, L.L.,Sobolevsky, A.I. (deposition date: 2018-07-11, release date: 2018-08-22, Last modification date: 2024-03-13)

• Primary citation: Singh, A.K.,McGoldrick, L.L.,Twomey, E.C.,Sobolevsky, A.I.; Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6.; Sci Adv, 4:eaau6088-eaau6088, 2018; PubMed: 30116787; DOI: 10.1126/sciadv.aau6088

Experimental method

ELECTRON MICROSCOPY (3.9 Å)