7T37

Activated state of 2-APB and CBD-bound wildtype rat TRPV2 in nanodiscs

Summary for 7T37

Entry DOI	10.2210/pdb7t37/pdb
EMDB information	25650 25651
Descriptor	Transient receptor potential cation channel subfamily V member 2, cannabidiol, 2-aminoethyl diphenylborinate (3 entities in total)
Functional Keywords	trp channel, ion channel, trpv, transport protein
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	4
Total formula weight	349353.79
Authors	Pumroy, R.A.,Protopopova, A.D.,Gallo, P.N.,Moiseenkova-Bell, V.Y. (deposition date: 2021-12-07, release date: 2022-05-04, Last modification date: 2024-02-28)
Primary citation	Pumroy, R.A.,Protopopova, A.D.,Fricke, T.C.,Lange, I.U.,Haug, F.M.,Nguyen, P.T.,Gallo, P.N.,Sousa, B.B.,Bernardes, G.J.L.,Yarov-Yarovoy, V.,Leffler, A.,Moiseenkova-Bell, V.Y. Structural insights into TRPV2 activation by small molecules. Nat Commun, 13:2334-2334, 2022 Cited by PubMed: 35484159 DOI: 10.1038/s41467-022-30083-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation