6YL2

Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism

Summary for 6YL2

• Entry DOI: 10.2210/pdb6yl2/pdb
• Related: 6YJ2
• Descriptor: Probable transcriptional regulatory protein (Probably TetR-family), DNA (5'-D(*AP*CP*GP*TP*TP*AP*AP*TP*GP*AP*CP*GP*AP*TP*TP*AP*AP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*TP*TP*AP*AP*TP*CP*GP*TP*CP*AP*TP*TP*AP*AP*CP*GP*T)-3') (3 entities in total)
• Functional Keywords: tuberculosis, branch-chain amino acid catabolism, tetr family, dna binding protein
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 4
• Total formula weight: 54779.05

Authors

Keep, N.H.,Pritchard, J.E.,Sula, A.,Cole, A.R.,Kendall, S.L. (deposition date: 2020-04-06, release date: 2021-04-14, Last modification date: 2024-01-24)

• Primary citation: Pritchard, J.E.,Sula, A.,Cole, A.R.,Kendall, S.L.,Keep, N.H.; Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism; To be published,

Experimental method

X-RAY DIFFRACTION (3.15 Å)