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4R9W

Crystal structure of platelet factor 4 complexed with fondaparinux

Summary for 4R9W
Entry DOI10.2210/pdb4r9w/pdb
Related4R97 4R9Y
Related PRD IDPRD_900028
DescriptorPlatelet factor 4, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside (3 entities in total)
Functional Keywordspf4, fondaparinux, cxc chemokine, platelet factor, glycosaminoglycan, platelet, cytokine
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight17072.65
Authors
Cai, Z.,Zhu, Z.,Liu, Q.,Greene, M.I. (deposition date: 2014-09-08, release date: 2015-12-16, Last modification date: 2020-07-29)
Primary citationCai, Z.,Yarovoi, S.V.,Zhu, Z.,Rauova, L.,Hayes, V.,Lebedeva, T.,Liu, Q.,Poncz, M.,Arepally, G.,Cines, D.B.,Greene, M.I.
Atomic description of the immune complex involved in heparin-induced thrombocytopenia.
Nat Commun, 6:8277-8277, 2015
Cited by
PubMed: 26391892
DOI: 10.1038/ncomms9277
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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